| Tag |
Content |
LipidDB ID |
LipidDB-9606-01403 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
4.39 |
Molecular Weight |
25205.8 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Transmembrane emp24 domain-containing protein 1 |
Protein Synonyms/Alias |
Interleukin-1 receptor-like 1 ligand; Putative T1/ST2 receptor-binding protein; p24 family protein gamma-1; Tp24; p24gamma1; |
Gene Name |
TMED1 |
Gene Synonyms/Alias |
IL1RL1L; IL1RL1LG; |
Created Date |
05-SEP-2006 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
213 | Canonical | LVAVLQVCTLKRFFQ | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. |
Sequence Annotation |
Topological domain: 24 194 Extracellular.
Transmembrane: 195 215 Helical.
Topological domain: 216 227 Cytoplasmic.
Domain: 43 125 GOLD.
Motif: 218 227 COPI vesicle coat-binding.
Motif: 218 219 COPII vesicle coat-binding.
|
Protein Length |
227 AA. |
Protein Sequence
(Canonical) |
MMAAGAALAL ALWLLMPPVE VGGAGPPPIQ DGEFTFLLPA GRKQCFYQSA PANASLETEY 60
QVIGGAGLDV DFTLESPQGV LLVSESRKAD GVHTVEPTEA GDYKLCFDNS FSTISEKLVF 120
FELIFDSLQD DEEVEGWAEA VEPEEMLDVK MEDIKESIET MRTRLERSIQ MLTLLRAFEA 180
RDRNLQEGNL ERVNFWSAVN VAVLLLVAVL QVCTLKRFFQ DKRPVPT 227
|
FASTA
(Canonical) |
>LipidDB-9606-01403|Q13445
MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEY
QVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF
FELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEA
RDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
|
Gene Ontology |
GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB GO:0005794; C:Golgi apparatus; IDA:UniProtKB GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0005886; C:plasma membrane; IEA:UniProtKB-KW GO:0005102; F:receptor binding; TAS:ProtInc GO:0007267; P:cell-cell signaling; TAS:ProtInc GO:0015031; P:protein transport; IEA:UniProtKB-KW GO:0007165; P:signal transduction; TAS:ProtInc |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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