LipidDB-9606-01392

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-9606-01392

Entry Name

RAB5C_HUMAN

UniProt Accession

P51148; F8W1H5; Q6FH55; Q9P0Y5;

Theoretical PI

8.64

Molecular Weight

23482.56

Genbank Protein ID

AAB08927.1; AAA74081.1; AAF66594.1; AAM21086.1; CAG46699.1; AAV38291.1; EAW60805.1; AAI06040.1; AAI14440.1;

Genbank Nucleotide ID

U18420; U11293; AF141304; AF498938; AK310234; CR541901; BT019484; AC003104; AC099811; AC105024; CH471152; BC106039; BC114439;

Protein Name

Ras-related protein Rab-5C

Protein Synonyms/Alias

L1880; RAB5L;

Gene Name

RAB5C

Gene Synonyms/Alias

RABL;

Created Date

01-OCT-1996

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
20	Canonical	PAAGNKICQFKLVLL	[1]	S-Palmitoylation
213	Canonical	NPASRSQCCSN****	[1]	S-Palmitoylation

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Reference

[1] Predicted from GPS-Lipid

Functional Description

Protein transport. Probably involved in vesicular traffic (By similarity).

Sequence Annotation

Nucleotide-binding: 28 35 GTP.
Nucleotide-binding: 76 80 GTP.
Nucleotide-binding: 134 137 GTP.
Motif: 50 58 Effector region.

Protein Length

216 AA.

Protein Sequence
(Canonical)

MAGRGGAARP NGPAAGNKIC QFKLVLLGES AVGKSSLVLR FVKGQFHEYQ ESTIGAAFLT  60
QTVCLDDTTV KFEIWDTAGQ ERYHSLAPMY YRGAQAAIVV YDITNTDTFA RAKNWVKELQ  120
RQASPNIVIA LAGNKADLAS KRAVEFQEAQ AYADDNSLLF METSAKTAMN VNEIFMAIAK  180
KLPKNEPQNA TGAPGRNRGV DLQENNPASR SQCCSN                            216

FASTA
(Canonical)

>LipidDB-9606-01392|P51148
MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLT
QTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQ
RQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAK
KLPKNEPQNATGAPGRNRGVDLQENNPASRSQCCSN

Gene Ontology

GO:0030139; C:endocytic vesicle; IEA:Ensembl
GO:0005768; C:endosome; IEA:UniProtKB-KW
GO:0070062; C:extracellular vesicular exosome; IDA:UniProtKB
GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA
GO:0005811; C:lipid particle; IDA:UniProtKB
GO:0005765; C:lysosomal membrane; IDA:UniProtKB
GO:0005886; C:plasma membrane; IEA:UniProtKB-KW
GO:0019003; F:GDP binding; IDA:UniProtKB
GO:0005525; F:GTP binding; IEA:UniProtKB-KW
GO:0003924; F:GTPase activity; IDA:UniProtKB
GO:0007032; P:endosome organization; IEA:Ensembl
GO:0006184; P:GTP catabolic process; IDA:UniProtKB
GO:0048227; P:plasma membrane to endosome transport; IMP:UniProtKB
GO:0015031; P:protein transport; IEA:UniProtKB-KW
GO:0030100; P:regulation of endocytosis; IEA:Ensembl
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro

Interpro

InterPro; IPR027417; P-loop_NTPase
InterPro; IPR005225; Small_GTP-bd_dom
InterPro; IPR001806; Small_GTPase
InterPro; IPR003579; Small_GTPase_Rab_type

Pfam

Pfam; PF00071; Ras;

SMART

SMART; SM00175; RAB;

PROSITE

PROSITE; PS51419; RAB;

PRINTS

PRINTS; PR00449; RASTRNSFRMNG;