LipidDB-9606-01290

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-9606-01290

Entry Name

MLEC_HUMAN

UniProt Accession

Q14165;

Theoretical PI

5.27

Molecular Weight

32233.87

Genbank Protein ID

BAA09773.2; AAH00371.1; AAH16297.1;

Genbank Nucleotide ID

D63486; BC000371; BC016297;

Protein Name

Malectin

Protein Synonyms/Alias

Gene Name

MLEC

Gene Synonyms/Alias

KIAA0152;

Created Date

01-NOV-1997

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
288	Canonical	VFIPTLFCLCRL***	[1]	S-Palmitoylation

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Reference

[1] Predicted from GPS-Lipid

Functional Description

Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity).

Sequence Annotation

Topological domain: 29 269 Lumenal.
Transmembrane: 270 290 Helical.
Topological domain: 291 292 Cytoplasmic.
Binding site: 82 82 Carbohydrate.
Binding site: 104 104 Carbohydrate.
Binding site: 131 131 Carbohydrate.
Binding site: 132 132 Carbohydrate.
Binding site: 201 201 Carbohydrate.

Protein Length

292 AA.

Protein Sequence
(Canonical)

MLGAWAVEGT AVALLRLLLL LLPPAIRGPG LGVAGVAGAA GAGLPESVIW AVNAGGEAHV  60
DVHGIHFRKD PLEGRVGRAS DYGMKLPILR SNPEDQILYQ TERYNEETFG YEVPIKEEGD  120
YVLVLKFAEV YFAQSQQKVF DVRLNGHVVV KDLDIFDRVG HSTAHDEIIP MSIRKGKLSV  180
QGEVSTFTGK LYIEFVKGYY DNPKVCALYI MAGTVDDVPK LQPHPGLEKK EEEEEEEEYD  240
EGSNLKKQTN KNRVQSGPRT PNPYASDNSS LMFPILVAFG VFIPTLFCLC RL          292

FASTA
(Canonical)

>LipidDB-9606-01290|Q14165
MLGAWAVEGTAVALLRLLLLLLPPAIRGPGLGVAGVAGAAGAGLPESVIWAVNAGGEAHV
DVHGIHFRKDPLEGRVGRASDYGMKLPILRSNPEDQILYQTERYNEETFGYEVPIKEEGD
YVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSV
QGEVSTFTGKLYIEFVKGYYDNPKVCALYIMAGTVDDVPKLQPHPGLEKKEEEEEEEEYD
EGSNLKKQTNKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL

Gene Ontology

GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB
GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0016020; C:membrane; IDA:UniProtKB
GO:0030246; F:carbohydrate binding; ISS:UniProtKB
GO:0019899; F:enzyme binding; IPI:UniProt
GO:0044267; P:cellular protein metabolic process; TAS:Reactome
GO:0043687; P:post-translational protein modification; TAS:Reactome
GO:0006457; P:protein folding; TAS:Reactome
GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome

Interpro

InterPro; IPR021720; Malectin

Pfam

Pfam; PF11721; Malectin;

SMART

PROSITE

PRINTS