| Tag |
Content |
LipidDB ID |
LipidDB-9606-01168 |
Entry Name |
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UniProt Accession |
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Theoretical PI |
8.29 |
Molecular Weight |
71438.88 |
Genbank Protein ID |
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Genbank Nucleotide ID |
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Protein Name |
Lipolysis-stimulated lipoprotein receptor |
Protein Synonyms/Alias |
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Gene Name |
LSR |
Gene Synonyms/Alias |
LISCH; |
Created Date |
11-JUL-2006 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
280 | Canonical | IFLLLGICWCQCCPH | [1] | S-Palmitoylation | 282 | Canonical | LLLGICWCQCCPHTC | [1] | S-Palmitoylation | 284 | Canonical | LGICWCQCCPHTCCC | [1] | S-Palmitoylation | 285 | Canonical | GICWCQCCPHTCCCY | [1] | S-Palmitoylation | 291 | Canonical | CCPHTCCCYVRCPCC | [1] | S-Palmitoylation | 295 | Canonical | TCCCYVRCPCCPDKC | [1] | S-Palmitoylation | 298 | Canonical | CYVRCPCCPDKCCCP | [1] | S-Palmitoylation | 302 | Canonical | CPCCPDKCCCPEALY | [1] | S-Palmitoylation | 303 | Canonical | PCCPDKCCCPEALYA | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). |
Sequence Annotation |
Topological domain: 1 259 Extracellular.
Transmembrane: 260 280 Helical.
Topological domain: 281 649 Cytoplasmic.
Domain: 86 234 Ig-like V-type.
Modified residue: 365 365 Phosphoserine.
Modified residue: 493 493 Phosphoserine.
Modified residue: 528 528 Phosphoserine.
Modified residue: 530 530 Phosphoserine.
Modified residue: 540 540 Phosphoserine.
Modified residue: 643 643 Phosphoserine.
|
Protein Length |
649 AA. |
Protein Sequence
(Canonical) |
MQQDGLGVGT RNGSGKGRSV HPSWPWCAPR PLRYFGRDAR ARRAQTAAMA LLAGGLSRGL 60
GSHPAAAGRD AVVFVWLLLS TWCTAPARAI QVTVSNPYHV VILFQPVTLP CTYQMTSTPT 120
QPIVIWKYKS FCRDRIADAF SPASVDNQLN AQLAAGNPGY NPYVECQDSV RTVRVVATKQ 180
GNAVTLGDYY QGRRITITGN ADLTFDQTAW GDSGVYYCSV VSAQDLQGNN EAYAELIVLG 240
RTSGVAELLP GFQAGPIEDW LFVVVVCLAA FLIFLLLGIC WCQCCPHTCC CYVRCPCCPD 300
KCCCPEALYA AGKAATSGVP SIYAPSTYAH LSPAKTPPPP AMIPMGPAYN GYPGGYPGDV 360
DRSSSAGGQG SYVPLLRDTD SSVASEVRSG YRIQASQQDD SMRVLYYMEK ELANFDPSRP 420
GPPSGRVERA MSEVTSLHED DWRSRPSRGP ALTPIRDEEW GGHSPRSPRG WDQEPAREQA 480
GGGWRARRPR ARSVDALDDL TPPSTAESGS RSPTSNGGRS RAYMPPRSRS RDDLYDQDDS 540
RDFPRSRDPH YDDFRSRERP PADPRSHHHR TRDPRDNGSR SGDLPYDGRL LEEAVRKKGS 600
EERRRPHKEE EEEAYYPPAP PPYSETDSQA SRERRLKKNL ALSRESLVV 649
|
FASTA
(Canonical) |
>LipidDB-9606-01168|Q86X29
MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG
RTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD
KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV
DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP
GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA
GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS
RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS
EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
|
Gene Ontology |
GO:0042627; C:chylomicron; IEA:UniProtKB-KW GO:0070062; C:extracellular vesicular exosome; IDA:UniProt GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW GO:0005886; C:plasma membrane; ISS:HGNC GO:0034361; C:very-low-density lipoprotein particle; IEA:UniProtKB-KW GO:0009790; P:embryo development; ISS:HGNC GO:0001889; P:liver development; ISS:HGNC |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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