| Tag |
Content |
LipidDB ID |
LipidDB-9606-01130 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.7 |
Molecular Weight |
32678.55 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Trem-like transcript 1 protein |
Protein Synonyms/Alias |
TLT-1; Triggering receptor expressed on myeloid cells-like protein 1; |
Gene Name |
TREML1 |
Gene Synonyms/Alias |
TLT1; UNQ1825/PRO3438; |
Created Date |
17-OCT-2006 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
196 | Canonical | QGNRLGVCGRFLSSR | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Dowal L, Yang W, Freeman MR, Steen H, Flaumenhaft R. Proteomic analysis ofpalmitoylated platelet proteins. Blood. 2011 Sep 29;118(13):e62-73. doi:10.1182/blood-2011-05-353078. Epub 2011 Aug 2.[ PMID:21813449]
|
Functional Description |
Cell surface receptor that may play a role in the innate and adaptive immune response. |
Sequence Annotation |
Topological domain: 16 162 Extracellular.
Transmembrane: 163 183 Helical.
Topological domain: 184 311 Cytoplasmic.
Domain: 16 121 Ig-like V-type.
Motif: 279 285 ITIM.
|
Protein Length |
311 AA. |
Protein Sequence
(Canonical) |
MGLTLLLLLL LGLEGQGIVG SLPEVLQAPV GSSILVQCHY RLQDVKAQKV WCRFLPEGCQ 60
PLVSSAVDRR APAGRRTFLT DLGGGLLQVE MVTLQEEDAG EYGCMVDGAR GPQILHRVSL 120
NILPPEEEEE THKIGSLAEN AFSDPAGSAN PLEPSQDEKS IPLIWGAVLL VGLLVAAVVL 180
FAVMAKRKQG NRLGVCGRFL SSRVSGMNPS SVVHHVSDSG PAAELPLDVP HIRLDSPPSF 240
DNTTYTSLPL DSPSGKPSLP APSSLPPLPP KVLVCSKPVT YATVIFPGGN KGGGTSCGPA 300
QNPPNNQTPS S 311
|
FASTA
(Canonical) |
>LipidDB-9606-01130|Q86YW5
MGLTLLLLLLLGLEGQGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQ
PLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSL
NILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIPLIWGAVLLVGLLVAAVVL
FAVMAKRKQGNRLGVCGRFLSSRVSGMNPSSVVHHVSDSGPAAELPLDVPHIRLDSPPSF
DNTTYTSLPLDSPSGKPSLPAPSSLPPLPPKVLVCSKPVTYATVIFPGGNKGGGTSCGPA
QNPPNNQTPSS
|
Gene Ontology |
GO:0009986; C:cell surface; IDA:UniProtKB GO:0016021; C:integral component of membrane; NAS:UniProtKB GO:0005886; C:plasma membrane; IEA:UniProtKB-KW GO:0031091; C:platelet alpha granule; IDA:UniProtKB GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB GO:0045087; P:innate immune response; NAS:UniProtKB GO:0030168; P:platelet activation; IEA:Ensembl |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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