| Tag |
Content |
LipidDB ID |
LipidDB-9606-01071 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
7.12 |
Molecular Weight |
95614.81 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Prickle-like protein 2 |
Protein Synonyms/Alias |
|
Gene Name |
PRICKLE2 |
Gene Synonyms/Alias |
|
Created Date |
01-FEB-2005 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
841 | Canonical | KRQKSKNCIIS**** | [1] | S-Farnesylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Maurer-Stroh S, Koranda M, Benetka W, Schneider G, Sirota FL, Eisenhaber F.Towards complete sets of farnesylated and geranylgeranylated proteins. PLoSComput Biol. 2007 Apr 6;3(4):e66. Epub 2007 Feb 23.[ PMID:17411337]
|
Functional Description |
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Sequence Annotation |
Domain: 18 126 PET.
Domain: 128 193 LIM zinc-binding 1.
Domain: 193 253 LIM zinc-binding 2.
Domain: 253 317 LIM zinc-binding 3.
Modified residue: 92 92 Phosphoserine.
Modified residue: 841 841 Cysteine methyl ester.
|
Protein Length |
844 AA. |
Protein Sequence
(Canonical) |
MVTVMPLEME KTISKLMFDF QRNSTSDDDS GCALEEYAWV PPGLKPEQVH QYYSCLPEEK 60
VPYVNSPGEK LRIKQLLHQL PPHDNEVRYC NSLDEEEKRE LKLFSSQRKR ENLGRGNVRP 120
FPVTMTGAIC EQCGGQINGG DIAVFASRAG HGVCWHPPCF VCTVCNELLV DLIYFYQDGK 180
IYCGRHHAEC LKPRCAACDE IIFADECTEA EGRHWHMKHF CCFECETVLG GQRYIMKEGR 240
PYCCHCFESL YAEYCDTCAQ HIGIDQGQMT YDGQHWHATE TCFCCAHCKK SLLGRPFLPK 300
QGQIFCSRAC SAGEDPNGSD SSDSAFQNAR AKESRRSAKI GKNKGKTEEP MLNQHSQLQV 360
SSNRLSADVD PLSLQMDMLS LSSQTPSLNR DPIWRSREEP YHYGNKMEQN QTQSPLQLLS 420
QCNIRTSYSP GGQGAGAQPE MWGKHFSNPK RSSSLAMTGH AGSFIKECRE DYYPGRLRSQ 480
ESYSDMSSQS FSETRGSIQV PKYEEEEEEE GGLSTQQCRT RHPISSLKYT EDMTPTEQTP 540
RGSMESLALS NATGLSADGG AKRQEHLSRF SMPDLSKDSG MNVSEKLSNM GTLNSSMQFR 600
SAESVRSLLS AQQYQEMEGN LHQLSNPIGY RDLQSHGRMH QSFDFDGGMA GSKLPGQEGV 660
RIQPMSERTR RRATSRDDNR RFRPHRSRRS RRSRSDNALH LASEREAISR LKDRPPLRAR 720
EDYDQFMRQR SFQESMGHGS RRDLYGQCPR TVSDLALQNA FGDRWGPYFA EYDWCSTCSS 780
SSESDNEGYF LGEPIPQPAR LRYVTSDELL HKYSSYGLPK SSTLGGRGQL HSRKRQKSKN 840
CIIS 844
|
FASTA
(Canonical) |
>LipidDB-9606-01071|Q7Z3G6
MVTVMPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEK
VPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRP
FPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGK
IYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGR
PYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPK
QGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQV
SSNRLSADVDPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPLQLLS
QCNIRTSYSPGGQGAGAQPEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRSQ
ESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQTP
RGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFR
SAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQEGV
RIQPMSERTRRRATSRDDNRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPPLRAR
EDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYDWCSTCSS
SSESDNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGLPKSSTLGGRGQLHSRKRQKSKN
CIIS
|
Gene Ontology |
GO:0016327; C:apicolateral plasma membrane; IEA:Ensembl GO:0005737; C:cytoplasm; IDA:LIFEdb GO:0016328; C:lateral plasma membrane; IEA:Ensembl GO:0005634; C:nucleus; IEA:UniProtKB-KW GO:0008270; F:zinc ion binding; IEA:InterPro GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl GO:0031175; P:neuron projection development; IEA:Ensembl |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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