| Tag |
Content |
LipidDB ID |
LipidDB-9606-00912 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
6.44 |
Molecular Weight |
40214.19 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Solute carrier family 35 member F6 |
Protein Synonyms/Alias |
ANT2-binding protein; ANT2BP; Transport and Golgi organization 9 homolog; |
Gene Name |
SLC35F6 |
Gene Synonyms/Alias |
C2orf18; UNQ3047/PRO9863; |
Created Date |
18-APR-2006 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
36 | Canonical | DNFMAEGCGGSKEHS | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter. |
Sequence Annotation |
Transmembrane: 48 68 Helical.
Transmembrane: 89 109 Helical.
Transmembrane: 117 137 Helical.
Transmembrane: 140 160 Helical.
Transmembrane: 176 196 Helical.
Transmembrane: 216 236 Helical.
Transmembrane: 261 281 Helical.
Transmembrane: 295 312 Helical.
Transmembrane: 317 336 Helical.
Domain: 104 160 EamA.
Modified residue: 365 365 Phosphothreonine.
|
Protein Length |
371 AA. |
Protein Sequence
(Canonical) |
MAWTKYQLFL AGLMLVTGSI NTLSAKWADN FMAEGCGGSK EHSFQHPFLQ AVGMFLGEFS 60
CLAAFYLLRC RAAGQSDSSV DPQQPFNPLL FLPPALCDMT GTSLMYVALN MTSASSFQML 120
RGAVIIFTGL FSVAFLGRRL VLSQWLGILA TIAGLVVVGL ADLLSKHDSQ HKLSEVITGD 180
LLIIMAQIIV AIQMVLEEKF VYKHNVHPLR AVGTEGLFGF VILSLLLVPM YYIPAGSFSG 240
NPRGTLEDAL DAFCQVGQQP LIAVALLGNI SSIAFFNFAG ISVTKELSAT TRMVLDSLRT 300
VVIWALSLAL GWEAFHALQI LGFLILLIGT ALYNGLHRPL LGRLSRGRPL AEESEQERLL 360
GGTRTPINDA S 371
|
FASTA
(Canonical) |
>LipidDB-9606-00912|Q8N357
MAWTKYQLFLAGLMLVTGSINTLSAKWADNFMAEGCGGSKEHSFQHPFLQAVGMFLGEFS
CLAAFYLLRCRAAGQSDSSVDPQQPFNPLLFLPPALCDMTGTSLMYVALNMTSASSFQML
RGAVIIFTGLFSVAFLGRRLVLSQWLGILATIAGLVVVGLADLLSKHDSQHKLSEVITGD
LLIIMAQIIVAIQMVLEEKFVYKHNVHPLRAVGTEGLFGFVILSLLLVPMYYIPAGSFSG
NPRGTLEDALDAFCQVGQQPLIAVALLGNISSIAFFNFAGISVTKELSATTRMVLDSLRT
VVIWALSLALGWEAFHALQILGFLILLIGTALYNGLHRPLLGRLSRGRPLAEESEQERLL
GGTRTPINDAS
|
Gene Ontology |
GO:0070062; C:extracellular vesicular exosome; IDA:UniProt GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0005765; C:lysosomal membrane; IDA:UniProtKB GO:0005739; C:mitochondrion; IDA:UniProtKB GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IMP:UniProtKB GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB GO:0006810; P:transport; IEA:UniProtKB-KW |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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