| Tag |
Content |
LipidDB ID |
LipidDB-9606-00812 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
4.79 |
Molecular Weight |
51871.99 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Protein disulfide-isomerase TMX3 |
Protein Synonyms/Alias |
5.3.4.1; Thioredoxin domain-containing protein 10; Thioredoxin-related transmembrane protein 3; |
Gene Name |
TMX3 |
Gene Synonyms/Alias |
KIAA1830; TXNDC10; |
Created Date |
10-MAY-2005 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
13 | Canonical | SWTALRLCATVVVLD | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. |
Sequence Annotation |
Topological domain: 25 375 Lumenal.
Transmembrane: 376 396 Helical.
Topological domain: 397 454 Cytoplasmic.
Domain: 25 128 Thioredoxin.
Motif: 451 454 Di-lysine motif.
|
Protein Length |
454 AA. |
Protein Sequence
(Canonical) |
MAAWKSWTAL RLCATVVVLD MVVCKGFVED LDESFKENRN DDIWLVDFYA PWCGHCKKLE 60
PIWNEVGLEM KSIGSPVKVG KMDATSYSSI ASEFGVRGYP TIKLLKGDLA YNYRGPRTKD 120
DIIEFAHRVS GALIRPLPSQ QMFEHMQKRH RVFFVYVGGE SPLKEKYIDA ASELIVYTYF 180
FSASEEVVPE YVTLKEMPAV LVFKDETYFV YDEYEDGDLS SWINRERFQN YLAMDGFLLY 240
ELGDTGKLVA LAVIDEKNTS VEHTRLKSII QEVARDYRDL FHRDFQFGHM DGNDYINTLL 300
MDELTVPTVV VLNTSNQQYF LLDRQIKNVE DMVQFINNIL DGTVEAQGGD SILQRLKRIV 360
FDAKSTIVSI FKSSPLMGCF LFGLPLGVIS IMCYGIYTAD TDGGYIEERY EVSKSENENQ 420
EQIEESKEQQ EPSSGGSVVP TVQEPKDVLE KKKD 454
|
FASTA
(Canonical) |
>LipidDB-9606-00812|Q96JJ7
MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV
FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ
EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
|
Gene Ontology |
GO:0009986; C:cell surface; IDA:MGI GO:0005783; C:endoplasmic reticulum; IBA:RefGenome GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome GO:0045454; P:cell redox homeostasis; IEA:InterPro GO:0006457; P:protein folding; IBA:RefGenome GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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