LipidDB-9606-00308

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-9606-00308

Entry Name

GAPR1_HUMAN

UniProt Accession

Q9H4G4; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36;

Theoretical PI

9.44

Molecular Weight

17218.31

Genbank Protein ID

CAC12812.1; AAK83460.1; BAC11019.1; BAC11395.1; CAH73678.1; AAH17918.1;

Genbank Nucleotide ID

AJ011129; AY039756; AK074488; AK075091; AL158830; BC017918;

Protein Name

Golgi-associated plant pathogenesis-related protein 1

Protein Synonyms/Alias

GAPR-1; Golgi-associated PR-1 protein; Glioma pathogenesis-related protein 2; GliPR 2;

Gene Name

GLIPR2

Gene Synonyms/Alias

C9orf19; GAPR1;

Created Date

29-MAR-2004

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
2	Canonical	******MGKSASKQF	[1]	N-Myristoylation

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Reference

[1] Eberle HB, Serrano RL, Füllekrug J, Schlosser A, Lehmann WD, Lottspeich F,Kaloyanova D, Wieland FT, Helms JB. Identification and characterization of anovel human plant pathogenesis-related protein that localizes to lipid-enrichedmicrodomains in the Golgi complex. J Cell Sci. 2002 Feb 15;115(Pt 4):827-38.[PMID:11865038]

Functional Description

Sequence Annotation

Domain: 14 132 SCP.
Region: 91 98 Interaction with CAV1.

Protein Length

154 AA.

Protein Sequence
(Canonical)

MGKSASKQFH NEVLKAHNEY RQKHGVPPLK LCKNLNREAQ QYSEALASTR ILKHSPESSR  60
GQCGENLAWA SYDQTGKEVA DRWYSEIKNY NFQQPGFTSG TGHFTAMVWK NTKKMGVGKA  120
SASDGSSFVV ARYFPAGNVV NEGFFEENVL PPKK                              154

FASTA
(Canonical)

>LipidDB-9606-00308|Q9H4G4
MGKSASKQFHNEVLKAHNEYRQKHGVPPLKLCKNLNREAQQYSEALASTRILKHSPESSR
GQCGENLAWASYDQTGKEVADRWYSEIKNYNFQQPGFTSGTGHFTAMVWKNTKKMGVGKA
SASDGSSFVVARYFPAGNVVNEGFFEENVLPPKK

Gene Ontology

GO:0070062; C:extracellular vesicular exosome; IDA:UniProtKB
GO:0000139; C:Golgi membrane; IDA:UniProt
GO:0042803; F:protein homodimerization activity; IDA:UniProt
GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProt
GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProt
GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProt

Interpro

InterPro; IPR001283; Allrgn_V5/Tpx1
InterPro; IPR018244; Allrgn_V5/Tpx1_CS
InterPro; IPR014044; CAP_domain

Pfam

Pfam; PF00188; CAP;

SMART

SMART; SM00198; SCP;

PROSITE

PROSITE; PS01009; CRISP_1;

PRINTS

PRINTS; PR00837; V5TPXLIKE;