| Tag |
Content |
LipidDB ID |
LipidDB-9606-00304 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.05 |
Molecular Weight |
34291.33 |
Genbank Protein ID |
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Genbank Nucleotide ID |
|
Protein Name |
DCN1-like protein 3 |
Protein Synonyms/Alias |
DCUN1 domain-containing protein 3; Defective in cullin neddylation protein 1-like protein 3; |
Gene Name |
DCUN1D3 |
Gene Synonyms/Alias |
|
Created Date |
26-FEB-2008 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
4 | Canonical | ****MGQCVTKCKNP | [1] | S-Palmitoylation | 8 | Canonical | MGQCVTKCKNPSSTL | [1] | S-Palmitoylation | 140 | Canonical | KFQAATMCKFTRKEF | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8- conjugating E2 enzyme UBE2F. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. |
Sequence Annotation |
Domain: 86 278 DCUN1.
|
Protein Length |
304 AA. |
Protein Sequence
(Canonical) |
MGQCVTKCKN PSSTLGSKNG DREPSNKSHS RRGAGHREEQ VPPCGKPGGD ILVNGTKKAE 60
AATEACQLPT SSGDAGRESK SNAEESSLQR LEELFRRYKD EREDAILEEG MERFCNDLCV 120
DPTEFRVLLL AWKFQAATMC KFTRKEFFDG CKAISADSID GICARFPSLL TEAKQEDKFK 180
DLYRFTFQFG LDSEEGQRSL HREIAIALWK LVFTQNNPPV LDQWLNFLTE NPSGIKGISR 240
DTWNMFLNFT QVIGPDLSNY SEDEAWPSLF DTFVEWEMER RKREGEGRGA LSSGPEGLCP 300
EEQT 304
|
FASTA
(Canonical) |
>LipidDB-9606-00304|Q8IWE4
MGQCVTKCKNPSSTLGSKNGDREPSNKSHSRRGAGHREEQVPPCGKPGGDILVNGTKKAE
AATEACQLPTSSGDAGRESKSNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCV
DPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFK
DLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISR
DTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREGEGRGALSSGPEGLCP
EEQT
|
Gene Ontology |
GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB GO:0010332; P:response to gamma radiation; IDA:UniProtKB GO:0010225; P:response to UV-C; IDA:UniProtKB |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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