| Tag |
Content |
LipidDB ID |
LipidDB-9606-00205 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
8.37 |
Molecular Weight |
53028.28 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Ancient ubiquitous protein 1 |
Protein Synonyms/Alias |
|
Gene Name |
AUP1 |
Gene Synonyms/Alias |
|
Created Date |
01-DEC-2000 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
54 | Canonical | IHVFLVSCALPDSVL | [1] | S-Palmitoylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. |
Sequence Annotation |
Topological domain: 1 20 Lumenal.
Transmembrane: 21 41 Helical; Signal-anchor for type IIImembrane protein.
Topological domain: 42 476 Cytoplasmic.
Domain: 362 404 CUE.
Modified residue: 1 1 N-acetylmethionine.
Modified residue: 354 354 Phosphoserine.
Modified residue: 358 358 Phosphoserine.
Modified residue: 429 429 Phosphoserine.
Modified residue: 433 433 Phosphothreonine.
|
Protein Length |
476 AA. |
Protein Sequence
(Canonical) |
MELPSGPGPE RLFDSHRLPG DCFLLLVLLL YAPVGFCLLV LRLFLGIHVF LVSCALPDSV 60
LRRFVVRTMC AVLGLVARQE DSGLRDHSVR VLISNHVTPF DHNIVNLLTT CSTVSESEAE 120
SATGRFPGAQ LKAPLSPLAF RMEDTEALPL TPILYPTCQF FFFIFLNIFL LAFSSPGSQP 180
LLNSPPSFVC WSRGFMEMNG RGELVESLKR FCASTRLPPT PLLLFPEEEA TNGREGLLRF 240
SSWPFSIQDV VQPLTLQVQR PLVSVTVSDA SWVSELLWSL FVPFTVYQVR WLRPVHRQLG 300
EANEEFALRV QQLVAKELGQ TGTRLTPADK AEHMKRQRHP RLRPQSAQSS FPPSPGPSPD 360
VQLATLAQRV KEVLPHVPLG VIQRDLAKTG CVDLTITNLL EGAVAFMPED ITKGTQSLPT 420
ASASKFPSSG PVTPQPTALT FAKSSWARQE SLQERKQALY EYARRRFTER RAQEAD 476
|
FASTA
(Canonical) |
>LipidDB-9606-00205|Q9Y679
MELPSGPGPERLFDSHRLPGDCFLLLVLLLYAPVGFCLLVLRLFLGIHVFLVSCALPDSV
LRRFVVRTMCAVLGLVARQEDSGLRDHSVRVLISNHVTPFDHNIVNLLTTCSTVSESEAE
SATGRFPGAQLKAPLSPLAFRMEDTEALPLTPILYPTCQFFFFIFLNIFLLAFSSPGSQP
LLNSPPSFVCWSRGFMEMNGRGELVESLKRFCASTRLPPTPLLLFPEEEATNGREGLLRF
SSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLRPVHRQLG
EANEEFALRVQQLVAKELGQTGTRLTPADKAEHMKRQRHPRLRPQSAQSSFPPSPGPSPD
VQLATLAQRVKEVLPHVPLGVIQRDLAKTGCVDLTITNLLEGAVAFMPEDITKGTQSLPT
ASASKFPSSGPVTPQPTALTFAKSSWARQESLQERKQALYEYARRRFTERRAQEAD
|
Gene Ontology |
GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0016020; C:membrane; IDA:UniProtKB |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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