LipidDB-9606-00109

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-9606-00109

Entry Name

RL3_HUMAN

UniProt Accession

P39023; B2RDV9; Q15548; Q5I0G0;

Theoretical PI

10.19

Molecular Weight

46108.89

Genbank Protein ID

CAA51839.1; BAB93474.1; CAG30452.1; BAG38056.1; CAA18450.1; AAH02408.1; AAH06483.1; AAH08003.1; AAH12146.1; AAH12786.1; AAH13674.1; AAH14017.1; AAH15032.1; AAH15767.1; AAH63662.1; AAH88373.1; AAI07712.1; AAA60291.1; AAA91344.1; BAA25828.1;

Genbank Nucleotide ID

X73460; AB062291; CR456566; AK315693; AL022326; BC002408; BC006483; BC008003; BC012146; BC012786; BC013674; BC014017; BC015032; BC015767; BC063662; BC088373; BC107711; M90054; L22453; AB007166;

Protein Name

60S ribosomal protein L3

Protein Synonyms/Alias

HIV-1 TAR RNA-binding protein B; TARBP-B;

Gene Name

RPL3

Gene Synonyms/Alias

OK/SW-cl.32;

Created Date

01-FEB-1995

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
157	Canonical	FSSMKKYCQVIRVIA	[1]	S-Palmitoylation

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Reference

[1] Predicted from GPS-Lipid

Functional Description

The L3 protein is a component of the large subunit of cytoplasmic ribosomes.

Sequence Annotation

Modified residue: 13 13 Phosphoserine.
Modified residue: 136 136 N6-acetyllysine.
Modified residue: 286 286 N6-acetyllysine.
Modified residue: 294 294 N6-acetyllysine.
Modified residue: 304 304 Phosphoserine.
Modified residue: 366 366 N6-acetyllysine.
Modified residue: 373 373 N6-acetyllysine.

Protein Length

403 AA.

Protein Sequence
(Canonical)

MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV  60
DRPGSKVNKK EVVEAVTIVE TPPMVVVGIV GYVETPRGLR TFKTVFAEHI SDECKRRFYK  120
NWHKSKKKAF TKYCKKWQDE DGKKQLEKDF SSMKKYCQVI RVIAHTQMRL LPLRQKKAHL  180
MEIQVNGGTV AEKLDWARER LEQQVPVNQV FGQDEMIDVI GVTKGKGYKG VTSRWHTKKL  240
PRKTHRGLRK VACIGAWHPA RVAFSVARAG QKGYHHRTEI NKKIYKIGQG YLIKDGKLIK  300
NNASTDYDLS DKSINPLGGF VHYGEVTNDF VMLKGCVVGT KKRVLTLRKS LLVQTKRRAL  360
EKIDLKFIDT TSKFGHGRFQ TMEEKKAFMG PLKKDRIAKE EGA                    403

FASTA
(Canonical)

>LipidDB-9606-00109|P39023
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREV
DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
NWHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHL
MEIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
NNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
EKIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA

Gene Ontology

GO:0005737; C:cytoplasm; IDA:HPA
GO:0005829; C:cytosol; TAS:Reactome
GO:0022625; C:cytosolic large ribosomal subunit; IDA:UniProtKB
GO:0070062; C:extracellular vesicular exosome; IDA:UniProt
GO:0005925; C:focal adhesion; IDA:UniProtKB
GO:0005730; C:nucleolus; IDA:UniProtKB
GO:0005634; C:nucleus; IDA:UniProt
GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB
GO:0003723; F:RNA binding; TAS:ProtInc
GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB
GO:0044267; P:cellular protein metabolic process; TAS:Reactome
GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl
GO:0010467; P:gene expression; TAS:Reactome
GO:0016071; P:mRNA metabolic process; TAS:Reactome
GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome
GO:0016070; P:RNA metabolic process; TAS:Reactome
GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome
GO:0006412; P:translation; NAS:UniProtKB
GO:0006414; P:translational elongation; TAS:Reactome
GO:0006413; P:translational initiation; TAS:Reactome
GO:0006415; P:translational termination; TAS:Reactome
GO:0019058; P:viral life cycle; TAS:Reactome
GO:0016032; P:viral process; TAS:Reactome
GO:0019083; P:viral transcription; TAS:Reactome

Interpro

InterPro; IPR000597; Ribosomal_L3
InterPro; IPR019926; Ribosomal_L3_CS
InterPro; IPR009000; Transl_B-barrel

Pfam

Pfam; PF00297; Ribosomal_L3;

SMART

PROSITE

PROSITE; PS00474; RIBOSOMAL_L3;

PRINTS