LipidDB ID

LipidDB-9606-00072

Entry Name

UniProt Accession

P99999; A4D166; B2R4I1; P00001; Q6NUR2; Q6NX69; Q96BV4;

Theoretical PI

9.59

Molecular Weight

11748.72

Genbank Protein ID

AAA35732.1; AAP35592.1; BAG34778.1; CAD28485.1; AAQ96844.1; EAL24239.1; EAW93822.1; AAH05299.1; AAH08475.1; AAH08477.1; AAH09578.1; AAH09579.1; AAH09582.1; AAH09587.1; AAH09602.1; AAH09607.1; AAH14359.1; AAH14361.1; AAH15130.1; AAH16006.1; AAH21994.1; AAH22330.1; AAH67222.1; AAH68464.1; AAH70156.1; AAH70346.1; AAH71761.1;

Genbank Nucleotide ID

M22877; BT006946; AK311836; AL713681; AC007487; CH236948; CH471073; BC005299; BC008475; BC008477; BC009578; BC009579; BC009582; BC009587; BC009602; BC009607; BC014359; BC014361; BC015130; BC016006; BC021994; BC022330; BC067222; BC068464; BC070156; BC070346; BC071761;

Protein Name

Cytochrome c

Protein Synonyms/Alias

Gene Name

CYCS

Gene Synonyms/Alias

CYC;

Created Date

21-JUL-1986

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Reference

[1] Predicted from GPS-Lipid

Functional Description

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.

Sequence Annotation

Metal binding site: 19 19 Iron (heme axial ligand).
Metal binding site: 81 81 Iron (heme axial ligand).
Binding site: 15 15 Heme (covalent).
Binding site: 18 18 Heme (covalent).
Modified residue: 2 2 N-acetylglycine.
Modified residue: 49 49 Phosphotyrosine.
Modified residue: 98 98 Phosphotyrosine.

Protein Length

105 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005829; C:cytosol; IMP:UniProtKB
GO:0005743; C:mitochondrial inner membrane; TAS:Reactome
GO:0005758; C:mitochondrial intermembrane space; TAS:UniProtKB
GO:0005739; C:mitochondrion; IDA:UniProt
GO:0005634; C:nucleus; IDA:LIFEdb
GO:0000159; C:protein phosphatase type 2A complex; TAS:UniProtKB
GO:0070469; C:respiratory chain; IEA:UniProtKB-KW
GO:0045155; F:electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; IDA:UniProtKB
GO:0020037; F:heme binding; TAS:UniProtKB
GO:0005506; F:iron ion binding; IEA:InterPro
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; TAS:UniProtKB
GO:0006309; P:apoptotic DNA fragmentation; IMP:UniProtKB
GO:0006915; P:apoptotic process; TAS:Reactome
GO:0044237; P:cellular metabolic process; TAS:Reactome
GO:0045333; P:cellular respiration; TAS:UniProtKB
GO:0016311; P:dephosphorylation; TAS:GOC
GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome
GO:0022904; P:respiratory electron transport chain; TAS:Reactome
GO:0044281; P:small molecule metabolic process; TAS:Reactome

Interpro

InterPro; IPR009056; Cyt_c-like_dom
InterPro; IPR002327; Cyt_c_1A/1B
InterPro; IPR003088; Cyt_c_dom

Pfam

Pfam; PF00034; Cytochrom_C;

SMART

PROSITE

PROSITE; PS51007; CYTC;

PRINTS

PRINTS; PR00604; CYTCHRMECIAB;