| Tag |
Content |
LipidDB ID |
LipidDB-9606-00004 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
9.79 |
Molecular Weight |
22541.0 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Ras-like protein family member 10A |
Protein Synonyms/Alias |
Ras-like protein RRP22; Ras-related protein on chromosome 22; |
Gene Name |
RASL10A |
Gene Synonyms/Alias |
RRP22; |
Created Date |
15-JUL-1998 |
| Lipid Modification Sites |
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
200 | Canonical | GALHPARCSLM**** | [1] | S-Farnesylation |
|
Organism |
Homo sapiens (Human) |
NCBI Taxa ID |
9606 |
Reference |
[1] Elam C, Hesson L, Vos MD, Eckfeld K, Ellis CA, Bell A, Krex D, Birrer MJ,Latif F, Clark GJ. RRP22 is a farnesylated, nucleolar, Ras-related protein withtumor suppressor potential. Cancer Res. 2005 Apr 15;65(8):3117-25.[ PMID:15833841]
|
Functional Description |
Potent inhibitor of cellular proliferation. |
Sequence Annotation |
Nucleotide-binding: 11 18 GTP. Nucleotide-binding: 59 62 GTP. Nucleotide-binding: 129 132 GTP. Region: 1 203 Small GTPase-like. Motif: 33 42 Effector region. Modified residue: 200 200 Cysteine methyl ester.
|
Protein Length |
203 AA. |
Protein Sequence (Canonical) |
MGGSLRVAVL GAPGVGKTAI IRQFLFGDYP ERHRPTDGPR LYRPAVLLDG AVYDLSIRDG 60
DVAGPGSSPG GPEEWPDAKD WSLQDTDAFV LVYDICSPDS FDYVKALRQR IAETRPAGAP 120
EAPILVVGNK RDRQRLRFGP RRALAALVRR GWRCGYLECS AKYNWHVLRL FRELLRCALV 180
RARPAHPALR LQGALHPARC SLM 203
|
FASTA (Canonical) |
>LipidDB-9606-00004|Q92737
MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP
EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALV
RARPAHPALRLQGALHPARCSLM
|
Gene Ontology |
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Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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