| Tag |
Content |
LipidDB ID |
LipidDB-9031-00934 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.96 |
Molecular Weight |
60002.11 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Proto-oncogene tyrosine-protein kinase Yrk |
Protein Synonyms/Alias |
2.7.10.2; Yes-related kinase; p60-Yrk; |
Gene Name |
YRK |
Gene Synonyms/Alias |
|
Created Date |
01-FEB-1994 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
2 | Canonical | ******MGCVHCKEK | [1] | N-Myristoylation |
|
Organism |
Gallus gallus (Chicken) |
NCBI Taxa ID |
9031 |
Reference |
[1] Johnson DR, Bhatnagar RS, Knoll LJ, Gordon JI. Genetic and biochemical studiesof protein N-myristoylation. Annu Rev Biochem. 1994;63:869-914. Review. PubMedPMID: 7979256.[ PMID:7979256]
|
Functional Description |
May participate in signaling pathways. |
Sequence Annotation |
Domain: 81 142 SH3.
Domain: 148 245 SH2.
Domain: 270 523 Protein kinase.
Nucleotide-binding: 276 284 ATP.
Active site: 389 389 Proton acceptor.
Binding site: 298 298 ATP.
Modified residue: 419 419 Phosphotyrosine; by autocatalysis.
Modified residue: 530 530 Phosphotyrosine.
|
Protein Length |
536 AA. |
Protein Sequence
(Canonical) |
MGCVHCKEKI SGKGQGGSGT GTPAHPPSQY DPDPTQLSGA FTHIPDFNNF HAAAVSPPVP 60
FSGPGFYPCN TLQAHSSITG GGVTLFIALY DYEARTEDDL SFQKGEKFHI INNTEGDWWE 120
ARSLSSGATG YIPSNYVAPV DSIQAEEWYF GKIGRKDAER QLLCHGNCRG TFLIRESETT 180
KGAYSLSIRD WDEAKGDHVK HYKIRKLDSG GYYITTRAQF DTIQQLVQHY IERAAGLCCR 240
LAVPCPKGTP KLADLSVKTK DVWEIPRESL QLLQKLGNGQ FGEVWMGTWN GTTKVAVKTL 300
KPGTMSPEAF LEEAQIMKRL RHDKLVQLYA VVSEEPIYIV TEFMSQGSLL DFLKDGDGRY 360
LKLPQLVDMA AQIAAGMAYI ERMNYIHRDL RAANILVGDN LVCKIADFGL ARLIEDNEYT 420
ARQGAKFPIK WTAPEAALFG KFTIKSDVWS FGILLTELVT KGRVPYPGMN NREVLEQVER 480
GYRMQCPGGC PPSLHDVMVQ CWKREPEERP TFEYLQSFLE DYFTATEPQY QPGDNQ 536
|
FASTA
(Canonical) |
>LipidDB-9031-00934|Q02977
MGCVHCKEKISGKGQGGSGTGTPAHPPSQYDPDPTQLSGAFTHIPDFNNFHAAAVSPPVP
FSGPGFYPCNTLQAHSSITGGGVTLFIALYDYEARTEDDLSFQKGEKFHIINNTEGDWWE
ARSLSSGATGYIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETT
KGAYSLSIRDWDEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHYIERAAGLCCR
LAVPCPKGTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGTTKVAVKTL
KPGTMSPEAFLEEAQIMKRLRHDKLVQLYAVVSEEPIYIVTEFMSQGSLLDFLKDGDGRY
LKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER
GYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ
|
Gene Ontology |
GO:0005524; F:ATP binding; IEA:UniProtKB-KW GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC GO:0045087; P:innate immune response; IEA:InterPro |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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