| Tag |
Content |
LipidDB ID |
LipidDB-9031-00681 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
9.16 |
Molecular Weight |
36837.66 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Protein Wnt-1 |
Protein Synonyms/Alias |
|
Gene Name |
WNT1 |
Gene Synonyms/Alias |
WNT-1; |
Created Date |
15-JUL-1998 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
60 | Canonical | LQSAVRECQWQFRNR | [1] | S-Palmitoylation |
|
Organism |
Gallus gallus (Chicken) |
NCBI Taxa ID |
9031 |
Reference |
[1] Galli LM, Burrus LW. Differential palmit(e)oylation of Wnt1 on C93 and S224residues has overlapping and distinct consequences. PLoS One. 2011;6(10):e26636. doi: 10.1371/journal.pone.0026636. Epub 2011 Oct 26.[ PMID:22046319]
|
Functional Description |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Proeminent role in the induction of the mesencephalon and cerebellum. |
Sequence Annotation |
|
Protein Length |
330 AA. |
Protein Sequence
(Canonical) |
WWGIVNVASS TNLLTDSGSV QLVLEPGLQL LSRKQRRLIR QNPGILHSVS AGLQSAVREC 60
QWQFRNRRWN CPTSQGPNIF GKIVNRGCRE TAFIFAITSA GVTHSVARSC SEGSIESCTC 120
DYRRRGPGGP DWHWGGCSDN IDFGRLFGRE FVDSSEKGRD LRFLMNLHNN EAGRMTVFSE 180
MRQECKCHGM SGSRTVRTCW MRLPTFRAVG DVLKDRFDGA SRVIYGNKGS NRASRVELHH 240
LEPENPAHKP PSPHDLVYFE KSPNFCTYSG KMGTAGTAGR ACNSSSPGLD GCELLCCGRG 300
FRTRTQRVTE RCNCTFHWCC HVSCLNCTNT 330
|
FASTA
(Canonical) |
>LipidDB-9031-00681|Q91029
WWGIVNVASSTNLLTDSGSVQLVLEPGLQLLSRKQRRLIRQNPGILHSVSAGLQSAVREC
QWQFRNRRWNCPTSQGPNIFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTC
DYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVDSSEKGRDLRFLMNLHNNEAGRMTVFSE
MRQECKCHGMSGSRTVRTCWMRLPTFRAVGDVLKDRFDGASRVIYGNKGSNRASRVELHH
LEPENPAHKPPSPHDLVYFEKSPNFCTYSGKMGTAGTAGRACNSSSPGLDGCELLCCGRG
FRTRTQRVTERCNCTFHWCCHVSCLNCTNT
|
Gene Ontology |
GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-KW GO:0006915; P:apoptotic process; TAS:AgBase GO:0030509; P:BMP signaling pathway; IDA:MGI GO:0048263; P:determination of dorsal identity; TAS:AgBase GO:0009953; P:dorsal/ventral pattern formation; TAS:AgBase GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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