LipidDB-7227-01440

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-7227-01440

Entry Name

Q8SX89_DROME

UniProt Accession

Q8SX89; Q9VEN4;

Theoretical PI

5.36

Molecular Weight

60159.98

Genbank Protein ID

AAF55387.2; AAM11131.1; AAN13733.1;

Genbank Nucleotide ID

AE014297; AY094778; AE014297;

Protein Name

Protein Synonyms/Alias

Kugelkern, isoform A; Kugelkern, isoform B; LD09231p;

Gene Name

kuk

Gene Synonyms/Alias

CG5175; GN Dmel_CG5175;

Created Date

01-JUN-2002

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
567	Canonical	AAEGRSICSIM****	[1]	S-Farnesylation

Organism

Drosophila melanogaster (Fruit fly)

NCBI Taxa ID

7227

Reference

[1] Brandt A, Krohne G, Grosshans J. The farnesylated nuclear proteins KUGELKERNand LAMIN B promote aging-like phenotypes in Drosophila flies. Aging Cell. 2008Aug;7(4):541-51. doi: 10.1111/j.1474-9726.2008.00406.x. Epub 2008 Jul 10.[PMID:18494863]

Functional Description

Sequence Annotation

Protein Length

570 AA.

Protein Sequence
(Canonical)

MLSKMASNTS GGGGTTSGTG TGRRLPLSLS GGSTVTRLQQ SSGSNGRSNS PQNGNKKITE  60
SFLPVKKSNQ PRTTSTGSTG SSQNGVSKPT NGKDKSQNGS STGKDQKVEK SKDKLPEKKA  120
KEVGAENKDK DGAAEMTDME VVVENKQKEV VSENKQNEVV SENKEVVSEN KEVVSENKEV  180
ASEKKVVVAE VPSDKDDNGE TKKDDATVES TAPASQTPAD AAVIIDEVVF IPDLSTPTKD  240
RKSTRKSGSQ QKSPISKASN ASPVQKIKTE AVSSSTSGSL TPQEDVDMEP LQVDASPIRS  300
VHGNLNAVPT ATSTPGRSLF SFRGSNKQST EVELAAQTSS SPAGTPARTF AQISGRRSIR  360
PIDSLTPSKI GTYRCGNSDL DTSNCTNASM NATVGSEIPN SSSFSFSFFG RGRKRERTPP  420
PLTASQSTSD LGHDVDMSPP KRARFDLFSL NLASPFSLLR SRFSKATIGT PTRLRLEPNS  480
SGVEEQHLNT STTGVPEEVD VEEEQPAEDV TVGQEAGAEE IPAKKDVEDK NVNGQDGDKE  540
SSDGENIDPV VEVADVAAVA AEGRSICSIM                                   570

FASTA
(Canonical)

>LipidDB-7227-01440|Q8SX89
MLSKMASNTSGGGGTTSGTGTGRRLPLSLSGGSTVTRLQQSSGSNGRSNSPQNGNKKITE
SFLPVKKSNQPRTTSTGSTGSSQNGVSKPTNGKDKSQNGSSTGKDQKVEKSKDKLPEKKA
KEVGAENKDKDGAAEMTDMEVVVENKQKEVVSENKQNEVVSENKEVVSENKEVVSENKEV
ASEKKVVVAEVPSDKDDNGETKKDDATVESTAPASQTPADAAVIIDEVVFIPDLSTPTKD
RKSTRKSGSQQKSPISKASNASPVQKIKTEAVSSSTSGSLTPQEDVDMEPLQVDASPIRS
VHGNLNAVPTATSTPGRSLFSFRGSNKQSTEVELAAQTSSSPAGTPARTFAQISGRRSIR
PIDSLTPSKIGTYRCGNSDLDTSNCTNASMNATVGSEIPNSSSFSFSFFGRGRKRERTPP
PLTASQSTSDLGHDVDMSPPKRARFDLFSLNLASPFSLLRSRFSKATIGTPTRLRLEPNS
SGVEEQHLNTSTTGVPEEVDVEEEQPAEDVTVGQEAGAEEIPAKKDVEDKNVNGQDGDKE
SSDGENIDPVVEVADVAAVAAEGRSICSIM

Gene Ontology

GO:0005811; C:lipid particle; IDA:FlyBase
GO:0005637; C:nuclear inner membrane; IDA:FlyBase
GO:0008344; P:adult locomotory behavior; IMP:FlyBase
GO:0007569; P:cell aging; IMP:FlyBase
GO:0007349; P:cellularization; IMP:FlyBase
GO:0016331; P:morphogenesis of embryonic epithelium; IMP:FlyBase
GO:0006997; P:nucleus organization; IMP:FlyBase

Interpro

Pfam

SMART

PROSITE

PRINTS