LipidDB ID

LipidDB-559292-01457

Entry Name

UniProt Accession

P31109; D6VPI8;

Theoretical PI

7.88

Molecular Weight

13201.27

Genbank Protein ID

AAA35069.1; AAC05002.1; DAA06958.1;

Genbank Nucleotide ID

M91157; U12980; BK006935;

Protein Name

Synaptobrevin homolog 1

Protein Synonyms/Alias

Gene Name

SNC1

Gene Synonyms/Alias

YAL030W;

Created Date

01-JUL-1993

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

NCBI Taxa ID

559292

Reference

[1] Valdez-Taubas J, Pelham H. Swf1-dependent palmitoylation of the SNARE Tlg1prevents its ubiquitination and degradation. EMBO J. 2005 Jul 20;24(14):2524-32. Epub 2005 Jun 23.[PMID:15973437]

Functional Description

SNC1 and SNC2 are vesicle-targeting proteins essential for normal secretory traffic between the Golgi and the plasma membrane. They may also be involved in vesicle fusion.

Sequence Annotation

Topological domain: 1 94 Cytoplasmic.
Transmembrane: 95 111 Helical; Anchor for type IV membraneprotein.
Topological domain: 112 117 Vesicular.
Domain: 28 88 v-SNARE coiled-coil homology.

Protein Length

117 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005935; C:cellular bud neck; IDA:SGD
GO:0005768; C:endosome; IDA:SGD
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0005886; C:plasma membrane; IDA:SGD
GO:0031201; C:SNARE complex; IDA:SGD
GO:0005802; C:trans-Golgi network; IDA:SGD
GO:0030658; C:transport vesicle membrane; IDA:SGD
GO:0005484; F:SNAP receptor activity; IDA:SGD
GO:0006897; P:endocytosis; IMP:SGD
GO:0006887; P:exocytosis; IMP:SGD
GO:0006893; P:Golgi to plasma membrane transport; IMP:SGD
GO:0006906; P:vesicle fusion; IDA:SGD

Interpro

InterPro; IPR001388; Synaptobrevin
InterPro; IPR016444; Synaptobrevin/VAMP_met/fun

Pfam

Pfam; PF00957; Synaptobrevin;

SMART

PROSITE

PROSITE; PS00417; SYNAPTOBREVIN;
PROSITE; PS50892; V_SNARE;

PRINTS

PRINTS; PR00219; SYNAPTOBREVN;