LipidDB-559292-01196

Lipid Modification Database

Tag

Content

LipidDB ID

Entry Name

GNP1_YEAST

UniProt Accession

P48813; D6VTD0;

Theoretical PI

7.84

Molecular Weight

73598.01

Genbank Protein ID

AAB48002.1; AAB64950.1; DAA12340.1;

Genbank Nucleotide ID

U21643; U33057; BK006938;

Protein Name

High-affinity glutamine permease

Protein Synonyms/Alias

Gene Name

GNP1

Gene Synonyms/Alias

YDR508C; D9719.14;

Created Date

01-FEB-1996

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
312	Canonical	ILAIIIDCGGAGTDG	[1]	S-Palmitoylation

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

NCBI Taxa ID

559292

Reference

[1] Predicted from GPS-Lipid

Functional Description

High affinity transport of glutamine. Also transport Leu, Ser, Thr, Cys, Met and Asn.

Sequence Annotation

Topological domain: 1 154 Cytoplasmic.
Transmembrane: 155 175 Helical.
Topological domain: 176 177 Mitochondrial intermembrane.
Transmembrane: 178 198 Helical.
Topological domain: 199 219 Cytoplasmic.
Transmembrane: 220 240 Helical.
Topological domain: 241 264 Mitochondrial intermembrane.
Transmembrane: 265 285 Helical.
Topological domain: 286 289 Cytoplasmic.
Transmembrane: 290 310 Helical.
Topological domain: 311 342 Mitochondrial intermembrane.
Transmembrane: 343 363 Helical.
Topological domain: 364 381 Cytoplasmic.
Transmembrane: 382 402 Helical.
Topological domain: 403 432 Mitochondrial intermembrane.
Transmembrane: 433 453 Helical.
Topological domain: 454 481 Cytoplasmic.
Transmembrane: 482 502 Helical.
Topological domain: 503 506 Mitochondrial intermembrane.
Transmembrane: 507 527 Helical.
Topological domain: 528 560 Cytoplasmic.
Transmembrane: 561 581 Helical.
Topological domain: 582 590 Mitochondrial intermembrane.
Transmembrane: 591 611 Helical.
Topological domain: 612 663 Cytoplasmic.
Modified residue: 29 29 Phosphoserine.
Modified residue: 113 113 Phosphoserine.
Modified residue: 124 124 Phosphoserine.
Modified residue: 127 127 Phosphothreonine.

Protein Length

663 AA.

Protein Sequence
(Canonical)

MTLGNRRHGR NNEGSSNMNM NRNDLDDVSH YEMKEIQPKE KQIGSIEPEN EVEYFEKTVE  60
KTIENMEYEG EHHASYLRRF IDSFRRAEGS HANSPDSSNS NGTTPISTKD SSSQLDNELN  120
RKSSYITVDG IKQSPQEQEQ KQENLKKSIK PRHTVMMSLG TGIGTGLLVG NSKVLNNAGP  180
GGLIIGYAIM GSCVYCIIQA CGELAVIYSD LIGGFNTYPL FLVDPALGFS VAWLFCLQWL  240
CVCPLELVTA SMTIKYWTTS VNPDVFVVIF YVLIVVINVF GAKGYAEADF FFNCCKILMI  300
VGFFILAIII DCGGAGTDGY IGSKYWRDPG AFRGDTPIQR FKGVVATFVT AAFAFGMSEQ  360
LAMTASEQSN PRKAIPSAAK KMIYRILFVF LASLTLVGFL VPYTSDQLLG AAGSATKASP  420
YVIAVSSHGV RVVPHFINAV ILLSVLSVAN GAFYTSSRIL MSLAKQGNAP KCFDYIDREG  480
RPAAAMLVSA LFGVIAFCAS SKKEEDVFTW LLAISGLSQL FTWITICLSH IRFRRAMKVQ  540
GRSLGEVGYK SQVGVWGSAY AVLMMVLALI AQFWVAIAPI GGGGKLSAQS FFENYLAMPI  600
WIALYIFYKV WKKDWSLFIP ADKVDLVSHR NIFDEELLKQ EDEEYKERLR NGPYWKRVLD  660
FWC                                                                663

FASTA
(Canonical)

>LipidDB-559292-01196|P48813
MTLGNRRHGRNNEGSSNMNMNRNDLDDVSHYEMKEIQPKEKQIGSIEPENEVEYFEKTVE
KTIENMEYEGEHHASYLRRFIDSFRRAEGSHANSPDSSNSNGTTPISTKDSSSQLDNELN
RKSSYITVDGIKQSPQEQEQKQENLKKSIKPRHTVMMSLGTGIGTGLLVGNSKVLNNAGP
GGLIIGYAIMGSCVYCIIQACGELAVIYSDLIGGFNTYPLFLVDPALGFSVAWLFCLQWL
CVCPLELVTASMTIKYWTTSVNPDVFVVIFYVLIVVINVFGAKGYAEADFFFNCCKILMI
VGFFILAIIIDCGGAGTDGYIGSKYWRDPGAFRGDTPIQRFKGVVATFVTAAFAFGMSEQ
LAMTASEQSNPRKAIPSAAKKMIYRILFVFLASLTLVGFLVPYTSDQLLGAAGSATKASP
YVIAVSSHGVRVVPHFINAVILLSVLSVANGAFYTSSRILMSLAKQGNAPKCFDYIDREG
RPAAAMLVSALFGVIAFCASSKKEEDVFTWLLAISGLSQLFTWITICLSHIRFRRAMKVQ
GRSLGEVGYKSQVGVWGSAYAVLMMVLALIAQFWVAIAPIGGGGKLSAQSFFENYLAMPI
WIALYIFYKVWKKDWSLFIPADKVDLVSHRNIFDEELLKQEDEEYKERLRNGPYWKRVLD
FWC

Gene Ontology

GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0005739; C:mitochondrion; IEA:UniProtKB-KW
GO:0005886; C:plasma membrane; ISS:SGD
GO:0015171; F:amino acid transmembrane transporter activity; IDA:SGD
GO:0015193; F:L-proline transmembrane transporter activity; IGI:SGD
GO:0006865; P:amino acid transport; IDA:SGD
GO:0035524; P:proline transmembrane transport; IGI:GOC
GO:0055085; P:transmembrane transport; IDA:SGD

Interpro

InterPro; IPR004841; AA-permease/SLC12A_dom
InterPro; IPR002293; AA/rel_permease1
InterPro; IPR004762; Amino_acid_permease_fungi
InterPro; IPR004840; Amoino_acid_permease_CS

Pfam

Pfam; PF00324; AA_permease;

SMART

PROSITE

PROSITE; PS00218; AMINO_ACID_PERMEASE_1;

PRINTS