Lipid Modification Database
Tag Content
LipidDB ID
LipidDB-559292-01057
Entry Name
UniProt Accession
Theoretical PI
5.81
Molecular Weight
23337.77
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Rheb-like protein RHB1
Protein Synonyms/Alias
GTP-binding protein RSG1;
Gene Name
RHB1
Gene Synonyms/Alias
RSG1; YCR027C; YCR27C;
Created Date
01-MAY-1992
 Lipid Modification Sites 
 Position   Sequence Form   Peptide   References   Modification Type 
206
Canonical
DAENNNKCSIM****
[1]
S-Farnesylation
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
NCBI Taxa ID
559292
Reference
[1] Urano J, Tabancay AP, Yang W, Tamanoi F. The Saccharomyces cerevisiae RhebG-protein is involved in regulating canavanine resistance and arginine uptake. J Biol Chem. 2000 Apr 14;275(15):11198-206.[PMID:10753927]
Functional Description
Involved in the regulation of arginine and lysine uptake. Acts through the CAN1 permease.
Sequence Annotation
Nucleotide-binding: 23 30 GTP.
Nucleotide-binding: 70 74 GTP.
Nucleotide-binding: 129 132 GTP.
Motif: 45 53 Effector region.
Modified residue: 1 1 N-acetylmethionine.
Modified residue: 206 206 Cysteine methyl ester.
Protein Length
209 AA.
Protein Sequence
(Canonical)
MEYATMSSSN STHNFQRKIA LIGARNVGKT TLTVRFVESR FVESYYPTIE NEFTRIIPYK  60
SHDCTLEILD TAGQDEVSLL NIKSLTGVRG IILCYSIINR ASFDLIPILW DKLVDQLGKD  120
NLPVILVGTK ADLGRSTKGV KRCVTKAEGE KLASTIGSQD KRNQAAFIEC SAELDYNVEE  180
TFMLLLKQME RVEGTLGLDA ENNNKCSIM                                    209
FASTA
(Canonical)
>LipidDB-559292-01057|P25378
MEYATMSSSNSTHNFQRKIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYK
SHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFDLIPILWDKLVDQLGKD
NLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEE
TFMLLLKQMERVEGTLGLDAENNNKCSIM
Gene Ontology
GO:0019897; C:extrinsic component of plasma membrane; IGI:SGD
GO:0005525; F:GTP binding; IEA:UniProtKB-KW
GO:0003924; F:GTPase activity; ISS:SGD
GO:0015809; P:arginine transport; IMP:SGD
GO:0015819; P:lysine transport; IMP:SGD
GO:0042147; P:retrograde transport, endosome to Golgi; IMP:SGD
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro
Interpro
InterPro; IPR027417; P-loop_NTPase
InterPro; IPR005225; Small_GTP-bd_dom
InterPro; IPR001806; Small_GTPase
InterPro; IPR020849; Small_GTPase_Ras
Pfam
Pfam; PF00071; Ras;
SMART
PROSITE
PROSITE; PS51421; RAS;
PRINTS
PRINTS; PR00449; RASTRNSFRMNG;