| Tag |
Content |
LipidDB ID |
LipidDB-559292-00937 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.25 |
Molecular Weight |
34346.59 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Ras-like protein 1 |
Protein Synonyms/Alias |
|
Gene Name |
RAS1 |
Gene Synonyms/Alias |
YOR101W; YOR3205W; |
Created Date |
21-JUL-1986 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
306 | Canonical | KESSGGCCIIC**** | [1] | S-Farnesylation |
|
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID |
559292 |
Reference |
[1] He B, Chen P, Chen SY, Vancura KL, Michaelis S, Powers S. RAM2, an essentialgene of yeast, and RAM1 encode the two polypeptide components of thefarnesyltransferase that prenylates a-factor and Ras proteins. Proc Natl Acad SciU S A. 1991 Dec 15;88(24):11373-7.[ PMID:1763050]
|
Functional Description |
The S.cerevisiae Ras proteins modulate the activity of the adenylate cyclase catalytic subunit and therefore affect the biosynthesis of cyclic-AMP. |
Sequence Annotation |
Nucleotide-binding: 17 24 GTP.
Nucleotide-binding: 64 68 GTP.
Nucleotide-binding: 123 126 GTP.
Motif: 39 47 Effector region.
Modified residue: 306 306 Cysteine methyl ester.
|
Protein Length |
309 AA. |
Protein Sequence
(Canonical) |
MQGNKSTIRE YKIVVVGGGG VGKSALTIQF IQSYFVDEYD PTIEDSYRKQ VVIDDKVSIL 60
DILDTAGQEE YSAMREQYMR TGEGFLLVYS VTSRNSFDEL LSYYQQIQRV KDSDYIPVVV 120
VGNKLDLENE RQVSYEDGLR LAKQLNAPFL ETSAKQAINV DEAFYSLIRL VRDDGGKYNS 180
MNRQLDNTNE IRDSELTSSA TADREKKNNG SYVLDNSLTN AGTGSSSKSA VNHNGETTKR 240
TDEKNYVNQN NNNEGNTKYS SNGNGNRSDI SRGNQNNALN SRSKQSAEPQ KNSSANARKE 300
SSGGCCIIC 309
|
FASTA
(Canonical) |
>LipidDB-559292-00937|P01119
MQGNKSTIREYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSIL
DILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVV
VGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNS
MNRQLDNTNEIRDSELTSSATADREKKNNGSYVLDNSLTNAGTGSSSKSAVNHNGETTKR
TDEKNYVNQNNNNEGNTKYSSNGNGNRSDISRGNQNNALNSRSKQSAEPQKNSSANARKE
SSGGCCIIC
|
Gene Ontology |
GO:0005886; C:plasma membrane; IDA:SGD GO:0005525; F:GTP binding; IEA:UniProtKB-KW GO:0003924; F:GTPase activity; IDA:SGD GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:SGD GO:0045762; P:positive regulation of adenylate cyclase activity; IGI:SGD GO:0097271; P:protein localization to bud neck; IGI:SGD GO:0001302; P:replicative cell aging; IMP:SGD GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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