| Tag |
Content |
LipidDB ID |
LipidDB-559292-00565 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
7.85 |
Molecular Weight |
68757.56 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Valine/tyrosine/tryptophan amino-acid permease 1 |
Protein Synonyms/Alias |
Tyrosine and tryptophan amino acid transporter 1; |
Gene Name |
TAT1 |
Gene Synonyms/Alias |
TAP1; VAP1; YBR069C; YBR0710; |
Created Date |
01-OCT-1994 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
141 | Canonical | IASIMLYCIIQAAGE | [1] | S-Palmitoylation |
|
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID |
559292 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
High-affinity transport of valine and tyrosine. Low- affinity transport of tryptophan. Can also transport L-cysteine. |
Sequence Annotation |
Topological domain: 1 99 Cytoplasmic.
Transmembrane: 100 120 Helical.
Topological domain: 121 122 Extracellular.
Transmembrane: 123 143 Helical.
Topological domain: 144 172 Cytoplasmic.
Transmembrane: 173 193 Helical.
Topological domain: 194 204 Extracellular.
Transmembrane: 205 225 Helical.
Topological domain: 226 233 Cytoplasmic.
Transmembrane: 234 254 Helical.
Topological domain: 255 281 Extracellular.
Transmembrane: 282 302 Helical.
Topological domain: 303 320 Cytoplasmic.
Transmembrane: 321 341 Helical.
Topological domain: 342 368 Extracellular.
Transmembrane: 369 389 Helical.
Topological domain: 390 422 Cytoplasmic.
Transmembrane: 423 443 Helical.
Topological domain: 444 446 Extracellular.
Transmembrane: 447 467 Helical.
Topological domain: 468 499 Cytoplasmic.
Transmembrane: 500 520 Helical.
Topological domain: 521 529 Extracellular.
Transmembrane: 530 550 Helical.
Topological domain: 551 619 Cytoplasmic.
Modified residue: 13 13 Phosphoserine.
Modified residue: 80 80 Phosphoserine.
Modified residue: 84 84 Phosphoserine.
|
Protein Length |
619 AA. |
Protein Sequence
(Canonical) |
MDDSVSFIAK EASPAQYSHS LHERTHSEKQ KRDFTITEKQ DEVSGQTAEP RRTDSKSILQ 60
RKCKEFFDSF KRQLPPDRNS ELESQEKNNL TKSIKSRHLV MISLGTGIGT GLLVGNGQVL 120
GTAGPAGLVL GYGIASIMLY CIIQAAGELG LCYAGLTGNY TRYPSILVDP SLGFAVSVVY 180
TIQWLTVLPL QLVTAAMTVK YWTSVNADIF VAVVFVFVII INLFGSRGYA EAEFIFNSCK 240
ILMVIGFVIL AIIINCGGAG DRRYIGAEYW HNPGPFAHGF KGVCTVFCYA AFSYGGIEVL 300
LLSAAEQENP TKSIPNACKK VVYRILLIYM LTTILVCFLV PYNSDELLGS SDSSGSHASP 360
FVIAVASHGV KVVPHFINAV ILISVISVAN SSLYSGPRLL LSLAEQGVLP KCLAYVDRNG 420
RPLLCFFVSL VFGCIGFVAT SDAEEQVFTW LLAISSLSQL FIWMSMSLSH IRFRDAMAKQ 480
GRSMNEVGYK AQTGYWGSWL AVLIAIFFLV CQFWVAIAPV NEHGKLNVKV FFQNYLAMPI 540
VLFAYFGHKI YFKSWSFWIP AEKIDLDSHR NIFVSPSLTE IDKVDDNDDL KEYENSESSE 600
NPNSSRSRKF FKRMTNFWC 619
|
FASTA
(Canonical) |
>LipidDB-559292-00565|P38085
MDDSVSFIAKEASPAQYSHSLHERTHSEKQKRDFTITEKQDEVSGQTAEPRRTDSKSILQ
RKCKEFFDSFKRQLPPDRNSELESQEKNNLTKSIKSRHLVMISLGTGIGTGLLVGNGQVL
GTAGPAGLVLGYGIASIMLYCIIQAAGELGLCYAGLTGNYTRYPSILVDPSLGFAVSVVY
TIQWLTVLPLQLVTAAMTVKYWTSVNADIFVAVVFVFVIIINLFGSRGYAEAEFIFNSCK
ILMVIGFVILAIIINCGGAGDRRYIGAEYWHNPGPFAHGFKGVCTVFCYAAFSYGGIEVL
LLSAAEQENPTKSIPNACKKVVYRILLIYMLTTILVCFLVPYNSDELLGSSDSSGSHASP
FVIAVASHGVKVVPHFINAVILISVISVANSSLYSGPRLLLSLAEQGVLPKCLAYVDRNG
RPLLCFFVSLVFGCIGFVATSDAEEQVFTWLLAISSLSQLFIWMSMSLSHIRFRDAMAKQ
GRSMNEVGYKAQTGYWGSWLAVLIAIFFLVCQFWVAIAPVNEHGKLNVKVFFQNYLAMPI
VLFAYFGHKIYFKSWSFWIPAEKIDLDSHRNIFVSPSLTEIDKVDDNDDLKEYENSESSE
NPNSSRSRKFFKRMTNFWC
|
Gene Ontology |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0005886; C:plasma membrane; IDA:SGD GO:0015171; F:amino acid transmembrane transporter activity; IDA:SGD GO:0022893; F:low-affinity tryptophan transmembrane transporter activity; IGI:SGD GO:0006865; P:amino acid transport; IDA:SGD GO:0055085; P:transmembrane transport; IDA:SGD GO:0015827; P:tryptophan transport; IGI:SGD GO:0015828; P:tyrosine transport; IMP:SGD |
Interpro |
|
Pfam |
|
SMART |
|
PROSITE |
PROSITE; PS00218; AMINO_ACID_PERMEASE_1; |
PRINTS |
|