LipidDB ID

LipidDB-559292-00432

Entry Name

UniProt Accession

Q00245; D6VVG9;

Theoretical PI

4.89

Molecular Weight

25312.39

Genbank Protein ID

BAA00897.1; CAA86874.1; AAS56183.1; DAA08435.1;

Genbank Nucleotide ID

D10006; Z46833; AY557857; BK006942;

Protein Name

GTP-binding protein RHO3

Protein Synonyms/Alias

Gene Name

RHO3

Gene Synonyms/Alias

YIL118W;

Created Date

01-DEC-1992

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

NCBI Taxa ID

559292

Reference

[1] Predicted from GPS-Lipid

Functional Description

Plays an important role in cell growth. Required to keep the uninucleated state. May be involved in the organization of the cytoskeleton which affects microtubule functions. Most likely RHO3 and RHO4 of S.cerevisiae regulate partially overlapping but different pathways.

Sequence Annotation

Nucleotide-binding: 23 30 GTP.
Nucleotide-binding: 70 74 GTP.
Nucleotide-binding: 128 131 GTP.
Motif: 45 53 Effector region.
Modified residue: 228 228 Cysteine methyl ester.

Protein Length

231 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005933; C:cellular bud; IDA:SGD
GO:0005829; C:cytosol; IDA:SGD
GO:0005886; C:plasma membrane; IEA:UniProtKB-KW
GO:0005525; F:GTP binding; IDA:SGD
GO:0003924; F:GTPase activity; IDA:SGD
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD
GO:0006184; P:GTP catabolic process; IDA:GOC
GO:0045921; P:positive regulation of exocytosis; IMP:SGD
GO:0090338; P:positive regulation of formin-nucleated actin cable assembly; IMP:SGD
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro

Interpro

InterPro; IPR027417; P-loop_NTPase
InterPro; IPR005225; Small_GTP-bd_dom
InterPro; IPR001806; Small_GTPase
InterPro; IPR003578; Small_GTPase_Rho

Pfam

Pfam; PF00071; Ras;

SMART

SMART; SM00174; RHO;

PROSITE

PROSITE; PS51420; RHO;

PRINTS

PRINTS; PR00449; RASTRNSFRMNG;