| Tag |
Content |
LipidDB ID |
LipidDB-559292-00273 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
4.93 |
Molecular Weight |
22129.46 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Trafficking protein particle complex subunit BET3 |
Protein Synonyms/Alias |
TRAPP subunit BET3; Transport protein particle 22 kDa subunit; |
Gene Name |
BET3 |
Gene Synonyms/Alias |
YKR068C; |
Created Date |
01-JUN-1994 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
80 | Canonical | ARTALPRCENLVKTS | [1] | S-Palmitoylation |
|
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID |
559292 |
Reference |
[1] Turnbull AP, Kümmel D, Prinz B, Holz C, Schultchen J, Lang C, Niesen FH,Hofmann KP, Delbrück H, Behlke J, Müller EC, Jarosch E, Sommer T, Heinemann U.Structure of palmitoylated BET3: insights into TRAPP complex assembly andmembrane localization. EMBO J. 2005 Mar 9;24(5):875-84. Epub 2005 Feb 3. PubMedPMID: 15692564; PubMed Central PMCID: PMC554119.[ PMID:15692564]
|
Functional Description |
Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II plays a role in intra-Golgi transport. TRAPP III plays a role in autophagosome formation. Required for sporulation. Has a role late in meiosis following DNA replication. |
Sequence Annotation |
|
Protein Length |
193 AA. |
Protein Sequence
(Canonical) |
MVSTTQSRSL KAMGEEIWKN KTEKINTELF TLTYGSIVAQ LCQDYERDFN KVNDHLYSMG 60
YNIGCRLIED FLARTALPRC ENLVKTSEVL SKCAFKIFLN ITPNITNWSH NKDTFSLILD 120
ENPLADFVEL PMDAMKSLWY SNILCGVLKG SLEMVQLDCD VWFVSDILRG DSQTEIKVKL 180
NRILKDEIPI GED 193
|
FASTA
(Canonical) |
>LipidDB-559292-00273|P36149
MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQDYERDFNKVNDHLYSMG
YNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNITPNITNWSHNKDTFSLILD
ENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCDVWFVSDILRGDSQTEIKVKL
NRILKDEIPIGED
|
Gene Ontology |
GO:0033106; C:cis-Golgi network membrane; IDA:SGD GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW GO:1990070; C:TRAPPI protein complex; IDA:SGD GO:1990071; C:TRAPPII protein complex; IDA:SGD GO:1990072; C:TRAPPIII protein complex; IDA:SGD GO:0042802; F:identical protein binding; IPI:IntAct GO:0006914; P:autophagy; IEA:UniProtKB-KW GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD GO:0032851; P:positive regulation of Rab GTPase activity; IDA:GOC |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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