| Tag |
Content |
LipidDB ID |
LipidDB-44689-00889 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
7.08 |
Molecular Weight |
13633.88 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Hisactophilin-2 |
Protein Synonyms/Alias |
Histidine-rich actin-binding protein 2; HS II; |
Gene Name |
hatB |
Gene Synonyms/Alias |
DDB_G0282143; |
Created Date |
01-NOV-1995 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
2 | Canonical | ******MGNRAFKAH | [1] | N-Myristoylation |
|
Organism |
Dictyostelium discoideum (Slime mold) |
NCBI Taxa ID |
44689 |
Reference |
[1] Hanakam F, Eckerskorn C, Lottspeich F, Müller-Taubenberger A, Schäfer W,Gerish G. The pH-sensitive actin-binding protein hisactophilin of Dictyosteliumexists in two isoforms which both are myristoylated and distributed betweenplasma membrane and cytoplasm. J Biol Chem. 1995 Jan 13;270(2):596-602. PubMedPMID: 7822284.[ PMID:7822284]
|
Functional Description |
May act as an intracellular pH sensor that links chemotactic signals to responses in the microfilament system of the cells by nucleating actin polymerization or stabilizing the filaments. |
Sequence Annotation |
Region: 8 109 Contains several HHXH repeats.
Region: 34 86 2 X 13 AA approximate repeats.
|
Protein Length |
118 AA. |
Protein Sequence
(Canonical) |
MGNRAFKAHN GHYLSAEHDH VKTHHGHHDH HTHFHIENHG SKVALRTHCG KYVSIGDHKQ 60
VYLSHHLHGD HSLFHLEHHH GKVSIKGHHH HYISVDGHGH VSTSHHHDHH ATFEEHIL 118
|
FASTA
(Canonical) |
>LipidDB-44689-00889|P42526
MGNRAFKAHNGHYLSAEHDHVKTHHGHHDHHTHFHIENHGSKVALRTHCGKYVSIGDHKQ
VYLSHHLHGDHSLFHLEHHHGKVSIKGHHHHYISVDGHGHVSTSHHHDHHATFEEHIL
|
Gene Ontology |
|
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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