LipidDB-3702-01439

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-3702-01439

Entry Name

UniProt Accession

Q941L3; Q9FH53;

Theoretical PI

5.66

Molecular Weight

63119.88

Genbank Protein ID

AAK98797.1; BAB08876.1; AED97534.1; AED97535.1; AAL32902.1; AAQ65178.1; AAM62570.1;

Genbank Nucleotide ID

AY045764; AB022212; CP002688; CP002688; AY062824; BT010555; AY085339;

Protein Name

Protein BONZAI 1

Protein Synonyms/Alias

COPINE 1;

Gene Name

BON1

Gene Synonyms/Alias

CPN1; At5g61900; K22G18.2;

Created Date

05-OCT-2010

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
2	Canonical	******MGNCCSDVA	[2]	N-Myristoylation
4	Canonical	****MGNCCSDVASG	[1]	S-Palmitoylation
5	Canonical	***MGNCCSDVASGA	[1]	S-Palmitoylation

Organism

Arabidopsis thaliana (Mouse-ear cress)

NCBI Taxa ID

3702

Reference

[1] Predicted from GPS-Lipid
[2] Li Y, Gou M, Sun Q, Hua J. Requirement of calcium binding, myristoylation, andprotein-protein interaction for the Copine BON1 function in Arabidopsis. J BiolChem. 2010 Sep 24;285(39):29884-91. doi: 10.1074/jbc.M109.066100. Epub 2010 Jul15.[PMID:20634289]

Functional Description

Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties.

Sequence Annotation

Domain: 34 147 C2 1.
Domain: 180 283 C2 2.
Domain: 341 560 VWFA.

Protein Length

578 AA.

Protein Sequence
(Canonical)

MGNCCSDVAS GAGATAGVGG SGSSAALGAT NDALDYYLKS KGFNGLFSQI ELSFSASNLR  60
DRDVLSKSDP MVVVYQKEKD ATLSEVFRSE VVLNSLAPKW IKKFIVAYHF ETVQTLVFRV  120
YDVDTKFQNS REEMLKLDEQ QFLGEATCAL SEIITKSTRT STLELKRKDG FAPQAQPHHG  180
KLIIHAEESL ASKISTEIVF RCSNLESKDL FSKSDPFLVV SKIVEHGTPI PVSKTEVRKN  240
DLNPIWKPVF LSVQQVGSKD SPVIIECSDF NSNGKHSLIG KVQKSLSDLE KLHLAGQGIN  300
FSLPTGAGQN KVLKSQLFVD KFTETVHHTF LEYLASGFEL NFMVAIDFTA SNGNPRLPDS  360
LHYIDPSGRL NAYQRAIMDV GEVLQFYDSD KRFPAWGFGA RPIDAPVSHC FNLNGSSSYS  420
EVDGIQGIMT SYTSALFNVS LAGPTLFGPV INAAAMIASA SLAQGSRKYY VLLIITDGVI  480
TDLQETKDAL VSASDLPLSI LIVGVGGADF KEMEILDADK GERLESSSGR LASRDIVQFV  540
ALRDVQYGEI SVVQALLAEL PSQFLTYMRI RNMKPIPP                          578
MGNCCSDVAS GAGATAGVGG SGSSAALGAT NDALDYYLKS KGFNGLFSQI ELSFSASNLR  60
DRDVLSKSDP MVVVYQKEKD ATLSEVFRSE VVLNSLAPKW IKKFIVAYHF ETVQTLVFRV  120
YDVDTKFQNS REEMLKLDEQ QFLGEATCAL SEIITKSTRT STLELKRKDG FAPQAQPHHG  180
KLIIHAEESL ASKISTEIVF RCSNLESKDL FSKSDPFLVV SKIVEHGTPI PVSKTEVRKN  240
DLNPIWKPVF LSVQQVGSKD SPVIIECSDF NSNGKHSLIG KVQKSLSDLE KLHLAGQGIN  300
FSLPTGAGQN KVLKSQLFVD KFTETVHHTF LEYLASGFEL NFMVAIDFTA SNGNPRLPDS  360
LHYIDPSGRL NAYQRAIMDV GEVLQFYDSD KRFPAWGFGA RPIDAPVSHC FNLNGSSSYS  420
EVDGIQGIMT SYTSALFNVS LAGPTLFGPV INAAAMIASA SLAQGSRKYY VLLIITDGVI  480
TDLQETKDAL VSASDLPLSI LIVGVGGADF KEMEILDADK GERLESSSGR LASRDIVQFV  540
ALRDVQYGEI SVVQALLAEL PSQFLTYMRI RNMKPIPP                          578

FASTA
(Canonical)

>LipidDB-3702-01439|Q941L3
MGNCCSDVASGAGATAGVGGSGSSAALGATNDALDYYLKSKGFNGLFSQIELSFSASNLR
DRDVLSKSDPMVVVYQKEKDATLSEVFRSEVVLNSLAPKWIKKFIVAYHFETVQTLVFRV
YDVDTKFQNSREEMLKLDEQQFLGEATCALSEIITKSTRTSTLELKRKDGFAPQAQPHHG
KLIIHAEESLASKISTEIVFRCSNLESKDLFSKSDPFLVVSKIVEHGTPIPVSKTEVRKN
DLNPIWKPVFLSVQQVGSKDSPVIIECSDFNSNGKHSLIGKVQKSLSDLEKLHLAGQGIN
FSLPTGAGQNKVLKSQLFVDKFTETVHHTFLEYLASGFELNFMVAIDFTASNGNPRLPDS
LHYIDPSGRLNAYQRAIMDVGEVLQFYDSDKRFPAWGFGARPIDAPVSHCFNLNGSSSYS
EVDGIQGIMTSYTSALFNVSLAGPTLFGPVINAAAMIASASLAQGSRKYYVLLIITDGVI
TDLQETKDALVSASDLPLSILIVGVGGADFKEMEILDADKGERLESSSGRLASRDIVQFV
ALRDVQYGEISVVQALLAELPSQFLTYMRIRNMKPIPP
MGNCCSDVASGAGATAGVGGSGSSAALGATNDALDYYLKSKGFNGLFSQIELSFSASNLR
DRDVLSKSDPMVVVYQKEKDATLSEVFRSEVVLNSLAPKWIKKFIVAYHFETVQTLVFRV
YDVDTKFQNSREEMLKLDEQQFLGEATCALSEIITKSTRTSTLELKRKDGFAPQAQPHHG
KLIIHAEESLASKISTEIVFRCSNLESKDLFSKSDPFLVVSKIVEHGTPIPVSKTEVRKN
DLNPIWKPVFLSVQQVGSKDSPVIIECSDFNSNGKHSLIGKVQKSLSDLEKLHLAGQGIN
FSLPTGAGQNKVLKSQLFVDKFTETVHHTFLEYLASGFELNFMVAIDFTASNGNPRLPDS
LHYIDPSGRLNAYQRAIMDVGEVLQFYDSDKRFPAWGFGARPIDAPVSHCFNLNGSSSYS
EVDGIQGIMTSYTSALFNVSLAGPTLFGPVINAAAMIASASLAQGSRKYYVLLIITDGVI
TDLQETKDALVSASDLPLSILIVGVGGADFKEMEILDADKGERLESSSGRLASRDIVQFV
ALRDVQYGEISVVQALLAELPSQFLTYMRIRNMKPIPP

Gene Ontology

GO:0005886; C:plasma membrane; IDA:TAIR
GO:0009506; C:plasmodesma; IDA:TAIR
GO:0005544; F:calcium-dependent phospholipid binding; IDA:TAIR
GO:0006952; P:defense response; IEA:UniProtKB-KW
GO:0060548; P:negative regulation of cell death; IMP:TAIR
GO:0045793; P:positive regulation of cell size; IMP:TAIR
GO:0009270; P:response to humidity; IMP:TAIR
GO:0009266; P:response to temperature stimulus; IEP:TAIR

Interpro

InterPro; IPR000008; C2_dom
InterPro; IPR010734; Copine
InterPro; IPR002035; VWF_A

Pfam

Pfam; PF00168; C2;
Pfam; PF07002; Copine;

SMART

SMART; SM00239; C2;
SMART; SM00327; VWA;

PROSITE

PROSITE; PS50004; C2;
PROSITE; PS50234; VWFA;

PRINTS