LipidDB ID

LipidDB-3702-01362

Entry Name

UniProt Accession

Q9FDX9; Q9LY73;

Theoretical PI

4.49

Molecular Weight

10947.38

Genbank Protein ID

AAG45959.1; AAG45960.1; CAB87795.1; AEE80479.1; AEE80480.1; BAD43578.1; ABD38879.1;

Genbank Nucleotide ID

AF283673; AF283674; AL163818; CP002686; CP002686; AK175815; BT024540;

Protein Name

Guanine nucleotide-binding protein subunit gamma 1

Protein Synonyms/Alias

Ggamma-subunit 1; Heterotrimeric G protein gamma-subunit 1; AtAGG1;

Gene Name

GG1

Gene Synonyms/Alias

AGG1; At3g63420; MAA21.50;

Created Date

31-OCT-2012

Organism

Arabidopsis thaliana (Mouse-ear cress)

NCBI Taxa ID

3702

Reference

[1] Zeng Q, Wang X, Running MP. Dual lipid modification of ArabidopsisGgamma-subunits is required for efficient plasma membrane targeting. PlantPhysiol. 2007 Mar;143(3):1119-31. Epub 2007 Jan 12.[PMID:17220359]

Functional Description

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Involved in the abscisic acid (ABA) and ethylene signaling pathways. Regulates acropetal transport of auxin (IAA) in roots and hypocotyls, and thus modulates root architecture (e.g. lateral root formation). The heterotrimeric G- protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression; involved in resistance to fungal pathogens such as Alternaria brassicicola, Plectosphaerella cucumerina and Fusarium oxysporum.

Sequence Annotation

Domain: 19 98 G protein gamma.
Region: 88 94 Regulates lipidation and cell membranesubcellular localization.
Modified residue: 95 95 Cysteine methyl ester.

Protein Length

98 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005737; C:cytoplasm; IDA:UniProtKB
GO:0005794; C:Golgi apparatus; IDA:UniProtKB
GO:0005834; C:heterotrimeric G-protein complex; IDA:UniProtKB
GO:0005886; C:plasma membrane; IDA:UniProtKB
GO:0005525; F:GTP binding; ISS:TAIR
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW
GO:0010541; P:acropetal auxin transport; IMP:TAIR
GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR
GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro
GO:0048527; P:lateral root development; IMP:TAIR
GO:0018345; P:protein palmitoylation; ISS:UniProtKB
GO:0018342; P:protein prenylation; ISS:UniProtKB
GO:0009845; P:seed germination; IMP:TAIR

Interpro

InterPro; IPR015898; G-protein_gamma-like_dom

Pfam

Pfam; PF00631; G-gamma;

SMART

PROSITE

PRINTS