| Tag |
Content |
LipidDB ID |
LipidDB-3702-01305 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
9.05 |
Molecular Weight |
37297.67 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Staphylococcal-like nuclease CAN2 |
Protein Synonyms/Alias |
3.1.31.-; Calcium-dependent nuclease 2; AtCAN2; Ca(2+)-dependent nuclease 2; |
Gene Name |
CAN2 |
Gene Synonyms/Alias |
At2g40410; T3G21.18; |
Created Date |
03-SEP-2014 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
12 | Canonical | LTFLYGKCCKPTTTD | [1] | S-Palmitoylation | 13 | Canonical | TFLYGKCCKPTTTDD | [1] | S-Palmitoylation |
|
Organism |
Arabidopsis thaliana (Mouse-ear cress) |
NCBI Taxa ID |
3702 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. Possesses activity toward the single-stranded DNA, double-stranded DNA and RNA. May be involved in genomic DNA degradation during programmed cell death. |
Sequence Annotation |
Domain: 140 316 TNase-like.
Active site: 223 223
Active site: 231 231
Active site: 265 265
Metal binding site: 153 153 Calcium.
Metal binding site: 228 228 Calcium.
|
Protein Length |
332 AA. |
Protein Sequence
(Canonical) |
MGNALTFLYG KCCKPTTTDD SLGPHGVSAA TVGVSALAHD LFNFEITSQV PEGLGRYVQS 60
SRKAQANWYR KILEAWKQAK PPPQTAEEAS RLVTDILKRN QKADVEGLLS FYGLPLSHTL 120
VEVTVEAPVS LPEGILFEFQ TLPVDPKAVA DGDTITVYVS TSEPVVSSSV PREVNLAAVQ 180
RAKAREKRNY PKADELHQKI IDSGYRVLNI ENEEVLARKF RIRLRGIDAP ESQMPFGKEA 240
QEGLLKIVGR KSLKVLVYGE DQYGRCVGDL YCNGIFVQEA MLKKGLAWHY LAYDKRPVLA 300
KWEKEARQKR IGLWASSNPE KPWDWRKNNR RE 332
|
FASTA
(Canonical) |
>LipidDB-3702-01305|F4IH31
MGNALTFLYGKCCKPTTTDDSLGPHGVSAATVGVSALAHDLFNFEITSQVPEGLGRYVQS
SRKAQANWYRKILEAWKQAKPPPQTAEEASRLVTDILKRNQKADVEGLLSFYGLPLSHTL
VEVTVEAPVSLPEGILFEFQTLPVDPKAVADGDTITVYVSTSEPVVSSSVPREVNLAAVQ
RAKAREKRNYPKADELHQKIIDSGYRVLNIENEEVLARKFRIRLRGIDAPESQMPFGKEA
QEGLLKIVGRKSLKVLVYGEDQYGRCVGDLYCNGIFVQEAMLKKGLAWHYLAYDKRPVLA
KWEKEARQKRIGLWASSNPEKPWDWRKNNRRE
|
Gene Ontology |
GO:0005886; C:plasma membrane; IEA:UniProtKB-KW GO:0004520; F:endodeoxyribonuclease activity; IDA:TAIR GO:0004521; F:endoribonuclease activity; IDA:TAIR GO:0046872; F:metal ion binding; IEA:UniProtKB-KW GO:0003676; F:nucleic acid binding; IEA:InterPro GO:0006308; P:DNA catabolic process; IDA:TAIR GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC GO:0006401; P:RNA catabolic process; IDA:TAIR GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC |
Interpro |
InterPro; IPR016071; Staphylococal_nuclease_OB-fold |
Pfam |
|
SMART |
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PROSITE |
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PRINTS |
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