Lipid Modification Database
Tag Content
LipidDB ID
LipidDB-3702-00327
Entry Name
UniProt Accession
Theoretical PI
9.24
Molecular Weight
23371.25
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
RPM1-interacting protein 4
Protein Synonyms/Alias
Gene Name
RIN4
Gene Synonyms/Alias
At3g25070; MJL12_1;
Created Date
11-APR-2003
 Lipid Modification Sites 
 Position   Sequence Form   Peptide   References   Modification Type 
204
Canonical
PNNTSSCCCFGFGGK
[1]
S-Palmitoylation
Organism
Arabidopsis thaliana (Mouse-ear cress)
NCBI Taxa ID
3702
Reference
[1] Predicted from GPS-Lipid
Functional Description
Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its association with avirulence proteins of the pathogen impairs the defense system and leads to the pathogen multiplication.
Sequence Annotation
Functional site: 10 11 Cleavage; by AvrRpt2.
Functional site: 152 153 Cleavage; by AvrRpt2.
Modified residue: 79 79 Phosphoserine.
Modified residue: 116 116 Phosphoserine.
Modified residue: 141 141 Phosphoserine.
Protein Length
211 AA.
Protein Sequence
(Canonical)
MARSNVPKFG NWEAEENVPY TAYFDKARKT RAPGSKIMNP NDPEYNSDSQ SQAPPHPPSS  60
RTKPEQVDTV RRSREHMRSR EESELKQFGD AGGSSNEAAN KRQGRASQNN SYDNKSPLHK  120
NSYDGTGKSR PKPTNLRADE SPEKVTVVPK FGDWDENNPS SADGYTHIFN KVREERSSGA  180
NVSGSSRTPT HQSSRNPNNT SSCCCFGFGG K                                 211
FASTA
(Canonical)
>LipidDB-3702-00327|Q8GYN5
MARSNVPKFGNWEAEENVPYTAYFDKARKTRAPGSKIMNPNDPEYNSDSQSQAPPHPPSS
RTKPEQVDTVRRSREHMRSREESELKQFGDAGGSSNEAANKRQGRASQNNSYDNKSPLHK
NSYDGTGKSRPKPTNLRADESPEKVTVVPKFGDWDENNPSSADGYTHIFNKVREERSSGA
NVSGSSRTPTHQSSRNPNNTSSCCCFGFGGK
Gene Ontology
GO:0019897; C:extrinsic component of plasma membrane; IDA:TAIR
GO:0016020; C:membrane; IDA:TAIR
GO:0005886; C:plasma membrane; IDA:TAIR
GO:0010204; P:defense response signaling pathway, resistance gene-independent; IMP:TAIR
GO:0009816; P:defense response to bacterium, incompatible interaction; IMP:TAIR
GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:TAIR
GO:0009626; P:plant-type hypersensitive response; IMP:TAIR
GO:0006468; P:protein phosphorylation; IDA:TAIR
GO:0002237; P:response to molecule of bacterial origin; IMP:TAIR
Interpro
InterPro; IPR008700; TypeIII_avirulence_cleave
Pfam
Pfam; PF05627; AvrRpt-cleavage;
SMART
PROSITE
PRINTS