| Tag |
Content |
LipidDB ID |
LipidDB-3702-00284 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
6.4 |
Molecular Weight |
64314.21 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Phosphoinositide phospholipase C 1 |
Protein Synonyms/Alias |
3.1.4.11; Phosphoinositide phospholipase PLC1; AtPLC1; AtPLC1S; PI-PLC1; |
Gene Name |
PLC1 |
Gene Synonyms/Alias |
ATHATPLC1G; At5g58670; MZN1.12; |
Created Date |
18-MAR-2008 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
8 | Canonical | MKESFKVCFCCVRNF | [1] | S-Palmitoylation | 10 | Canonical | ESFKVCFCCVRNFKV | [1] | S-Palmitoylation | 11 | Canonical | SFKVCFCCVRNFKVK | [1] | S-Palmitoylation | 505 | Canonical | VPELSLLCITVKDYD | [1] | S-Palmitoylation |
|
Organism |
Arabidopsis thaliana (Mouse-ear cress) |
NCBI Taxa ID |
3702 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Required for secondary responses to abscisic acid signals. |
Sequence Annotation |
Domain: 21 54 EF-hand.
Domain: 105 249 PI-PLC X-box.
Domain: 294 410 PI-PLC Y-box.
Domain: 417 524 C2.
Active site: 120 120
Active site: 166 166
|
Protein Length |
561 AA. |
Protein Sequence
(Canonical) |
MKESFKVCFC CVRNFKVKSS EPPEEIKNLF HDYSQDDRMS ADEMLRFVIQ VQGETHADIN 60
YVKDIFHRLK HHGVFHPRGI HLEGFYRYLL SDFNSPLPLT REVWQDMNQP LSHYFLYTGH 120
NSYLTGNQLN SNSSIEPIVK ALRNGVRVIE LDLWPNSSGK EAEVRHGGTL TSREDLQKCL 180
NVVKENAFQV SAYPVVLTLE DHLTPILQKK VAKMVSKTFG GSLFQCTDET TECFPSPESL 240
KNKILISTKP PKEYLQTQIS KGSTTDESTR AKKISDAEEQ VQEEDEESVA IEYRDLISIH 300
AGNRKGGLKN CLNGDPNRVI RLSMSEQWLE TLAKTRGPDL VKFTQRNLLR IFPKTTRFDS 360
SNYDPLVGWI HGAQMVAFNM QSHGRYLWMM QGMFKANGGC GYVKKPDVLL SNGPEGEIFD 420
PCSQNLPIKT TLKVKIYTGE GWNMDFPLDH FDRYSPPDFY AKVGIAGVPL DTASYRTEID 480
KDEWFPIWDK EFEFPLRVPE LSLLCITVKD YDSNTQNDFA GQTCFPLSEV RPGIRAVRLH 540
DRAGEVYKHV RLLMRFVLEP R 561
|
FASTA
(Canonical) |
>LipidDB-3702-00284|Q39032
MKESFKVCFCCVRNFKVKSSEPPEEIKNLFHDYSQDDRMSADEMLRFVIQVQGETHADIN
YVKDIFHRLKHHGVFHPRGIHLEGFYRYLLSDFNSPLPLTREVWQDMNQPLSHYFLYTGH
NSYLTGNQLNSNSSIEPIVKALRNGVRVIELDLWPNSSGKEAEVRHGGTLTSREDLQKCL
NVVKENAFQVSAYPVVLTLEDHLTPILQKKVAKMVSKTFGGSLFQCTDETTECFPSPESL
KNKILISTKPPKEYLQTQISKGSTTDESTRAKKISDAEEQVQEEDEESVAIEYRDLISIH
AGNRKGGLKNCLNGDPNRVIRLSMSEQWLETLAKTRGPDLVKFTQRNLLRIFPKTTRFDS
SNYDPLVGWIHGAQMVAFNMQSHGRYLWMMQGMFKANGGCGYVKKPDVLLSNGPEGEIFD
PCSQNLPIKTTLKVKIYTGEGWNMDFPLDHFDRYSPPDFYAKVGIAGVPLDTASYRTEID
KDEWFPIWDKEFEFPLRVPELSLLCITVKDYDSNTQNDFAGQTCFPLSEVRPGIRAVRLH
DRAGEVYKHVRLLMRFVLEPR
|
Gene Ontology |
GO:0005886; C:plasma membrane; IEA:UniProtKB-KW GO:0005509; F:calcium ion binding; IEA:InterPro GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC GO:0004629; F:phospholipase C activity; IDA:TAIR GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW GO:0009738; P:abscisic acid-activated signaling pathway; TAS:TAIR GO:0035556; P:intracellular signal transduction; IEA:InterPro GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW GO:0009737; P:response to abscisic acid; IMP:TAIR GO:0009409; P:response to cold; IEP:TAIR GO:0009651; P:response to salt stress; IEP:TAIR GO:0009414; P:response to water deprivation; IEP:TAIR |
Interpro |
|
Pfam |
|
SMART |
|
PROSITE |
|
PRINTS |
|