Lipid Modification Database
Tag Content
LipidDB ID
LipidDB-3702-00280
Entry Name
UniProt Accession
Theoretical PI
6.43
Molecular Weight
20608.64
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
ADP-ribosylation factor 1
Protein Synonyms/Alias
AtARF1;
Gene Name
ARF1
Gene Synonyms/Alias
At2g47170; T3D7.2; T8I13.1;
Created Date
01-JUN-1994
 Lipid Modification Sites 
 Position   Sequence Form   Peptide   References   Modification Type 
2
Canonical
******MGLSFGKLF
[1]
N-Myristoylation
Organism
Arabidopsis thaliana (Mouse-ear cress)
NCBI Taxa ID
3702
Reference
[1] Yamauchi S, Fusada N, Hayashi H, Utsumi T, Uozumi N, Endo Y, Tozawa Y. Theconsensus motif for N-myristoylation of plant proteins in a wheat germ cell-free translation system. FEBS J. 2010 Sep;277(17):3596-607. doi:10.1111/j.1742-4658.2010.07768.x.[PMID:20716180]
Functional Description
GTP-binding protein involved in protein trafficking; required for the sequence-specific vacuolar sorting route to the lytic vacuole, for the ER-to-Golgi transport and for the Golgi- derived transport to the plasma membrane. Involved in the recruitment of COPI and GDAP1 to membranes.
Sequence Annotation
Nucleotide-binding: 24 31 GTP.
Nucleotide-binding: 67 71 GTP.
Nucleotide-binding: 126 129 GTP.
Protein Length
181 AA.
Protein Sequence
(Canonical)
MGLSFGKLFS RLFAKKEMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG FNVETVEYKN  60
ISFTVWDVGG QDKIRPLWRH YFQNTQGLIF VVDSNDRDRV VEARDELHRM LNEDELRDAV  120
LLVFANKQDL PNAMNAAEIT DKLGLHSLRQ RHWYIQSTCA TSGEGLYEGL DWLSNNIASK  180
A                                                                  181
FASTA
(Canonical)
>LipidDB-3702-00280|P36397
MGLSFGKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAV
LLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASK
A
Gene Ontology
GO:0005768; C:endosome; IEA:UniProtKB-KW
GO:0005794; C:Golgi apparatus; IDA:TAIR
GO:0005525; F:GTP binding; ISS:TAIR
GO:0016004; F:phospholipase activator activity; TAS:TAIR
GO:0043085; P:positive regulation of catalytic activity; TAS:GOC
GO:0015031; P:protein transport; IEA:UniProtKB-KW
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro
GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW
Interpro
InterPro; IPR027417; P-loop_NTPase
InterPro; IPR005225; Small_GTP-bd_dom
InterPro; IPR024156; Small_GTPase_ARF
InterPro; IPR006689; Small_GTPase_ARF/SAR
Pfam
Pfam; PF00025; Arf;
SMART
SMART; SM00177; ARF;
PROSITE
PROSITE; PS51417; ARF;
PRINTS
PRINTS; PR00328; SAR1GTPBP;