Lipid Modification Database
Tag Content
LipidDB ID
LipidDB-36329-00932
Entry Name
UniProt Accession
Theoretical PI
8.87
Molecular Weight
48675.23
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Putative chloroquine resistance transporter
Protein Synonyms/Alias
PfCRT; Probable transporter cg10;
Gene Name
CG10
Gene Synonyms/Alias
MAL7P1.27;
Created Date
22-SEP-2009
 Lipid Modification Sites 
 Position   Sequence Form   Peptide   References   Modification Type 
301
Canonical
RNTVVENCGLGMAKL
[1]
S-Palmitoylation
Organism
Plasmodium falciparum (isolate 3D7)
NCBI Taxa ID
36329
Reference
[1] Predicted from GPS-Lipid
Functional Description
May regulate endogenous transporter.
Sequence Annotation
Topological domain: 1 58 Cytoplasmic.
Transmembrane: 59 79 Helical.
Topological domain: 80 90 Lumenal.
Transmembrane: 91 111 Helical.
Topological domain: 112 127 Cytoplasmic.
Transmembrane: 128 148 Helical.
Topological domain: 149 154 Lumenal.
Transmembrane: 155 175 Helical.
Topological domain: 176 178 Cytoplasmic.
Transmembrane: 179 199 Helical.
Topological domain: 200 209 Lumenal.
Transmembrane: 210 230 Helical.
Topological domain: 231 248 Cytoplasmic.
Transmembrane: 249 269 Helical.
Topological domain: 270 317 Lumenal.
Transmembrane: 318 338 Helical.
Topological domain: 339 346 Cytoplasmic.
Transmembrane: 347 367 Helical.
Topological domain: 368 377 Lumenal.
Transmembrane: 378 398 Helical.
Topological domain: 399 424 Cytoplasmic.
Protein Length
424 AA.
Protein Sequence
(Canonical)
MKFASKKNNQ KNSSKNDERY RELDNLVQEG NGSRLGGGSC LGKCAHVFKL IFKEIKDNIF  60
IYILSIIYLS VCVMNKIFAK RTLNKIGNYS FVTSETHNFI CMIMFFIVYS LFGNKKGNSK  120
ERHRSFNLQF FAISMLDACS VILAFIGLTR TTGNIQSFVL QLSIPINMFF CFLILRYRYH  180
LYNYLGAVII VVTIALVEMK LSFETQEENS IIFNLVLISA LIPVCFSNMT REIVFKKYKI  240
DILRLNAMVS FFQLFTSCLI LPVYTLPFLK QLHLPYNEIW TNIKNGFACL FLGRNTVVEN  300
CGLGMAKLCD DCDGAWKTFA LFSFFNICDN LITSYIIDKF STMTYTIVSC IQGPAIAIAY  360
YFKFLAGDVV REPRLLDFVT LFGYLFGSII YRVGNIILER KKMRNEENED SEGELTNVDS  420
IITQ                                                               424
FASTA
(Canonical)
>LipidDB-36329-00932|Q8IBZ9
MKFASKKNNQKNSSKNDERYRELDNLVQEGNGSRLGGGSCLGKCAHVFKLIFKEIKDNIF
IYILSIIYLSVCVMNKIFAKRTLNKIGNYSFVTSETHNFICMIMFFIVYSLFGNKKGNSK
ERHRSFNLQFFAISMLDACSVILAFIGLTRTTGNIQSFVLQLSIPINMFFCFLILRYRYH
LYNYLGAVIIVVTIALVEMKLSFETQEENSIIFNLVLISALIPVCFSNMTREIVFKKYKI
DILRLNAMVSFFQLFTSCLILPVYTLPFLKQLHLPYNEIWTNIKNGFACLFLGRNTVVEN
CGLGMAKLCDDCDGAWKTFALFSFFNICDNLITSYIIDKFSTMTYTIVSCIQGPAIAIAY
YFKFLAGDVVREPRLLDFVTLFGYLFGSIIYRVGNIILERKKMRNEENEDSEGELTNVDS
IITQ
Gene Ontology
GO:0005783; C:endoplasmic reticulum; IDA:GeneDB_Pfalciparum
GO:0020020; C:food vacuole; IDA:GeneDB_Pfalciparum
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0016020; C:membrane; TAS:GeneDB_Pfalciparum
GO:0015238; F:drug transmembrane transporter activity; TAS:GeneDB_Pfalciparum
GO:0006855; P:drug transmembrane transport; TAS:GOC
GO:0034635; P:glutathione transport; IDA:GeneDB_Pfalciparum
GO:0042493; P:response to drug; IDA:GeneDB_Pfalciparum
Interpro
InterPro; IPR000620; DMT
InterPro; IPR017258; Transprt_Chloroquine_res
Pfam
Pfam; PF00892; EamA;
SMART
PROSITE
PRINTS