| Tag |
Content |
LipidDB ID |
LipidDB-319-00189 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.55 |
Molecular Weight |
28703.78 |
Genbank Protein ID |
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Genbank Nucleotide ID |
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Protein Name |
28 kDa product |
Protein Synonyms/Alias |
3.4.22.-; |
Gene Name |
avrPph3 |
Gene Synonyms/Alias |
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Created Date |
01-NOV-1997 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
63 | Canonical | AMTLGDKGCASSSGV | [1] | N-Myristoylation |
|
Organism |
Pseudomonas syringae pv. phaseolicola |
NCBI Taxa ID |
319 |
Reference |
[1] Thieme F, Szczesny R, Urban A, Kirchner O, Hause G, Bonas U. New type IIIeffectors from Xanthomonas campestris pv. vesicatoria trigger plant reactionsdependent on a conserved N-myristoylation motif. Mol Plant Microbe Interact. 2007Oct;20(10):1250-61.[ PMID:17918627]
|
Functional Description |
Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana. The autocleavage of the protein is required for virulence function. May act by affecting the plant defense system. In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication. In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name. The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression. In infected plants, it probably acts by cleaving the PBS1 protein, which may lead to resistance or disease, depending on the presence or absence of RPS5, respectively. |
Sequence Annotation |
Functional site: 62 63 Cleavage; by autolysis.
|
Protein Length |
267 AA. |
Protein Sequence
(Canonical) |
MKIGTQATSL AVLHNQESHA PQAPIAVRPE PAHAIPEIPL DLAIRPRTRG IHPFLAMTLG 60
DKGCASSSGV SLEDDSHTQV SLSDFSVASR DVNHNNICAG LSTEWLVMSS DGDAESRMDH 120
LDYNGEGQSR GSERHQVYND ALRAALSNDD EAPFFTASTA VIEDAGFSLR REPKTVHASG 180
GSAQLGQTVA HDVAQSGRKH LLSLRFANVQ GHAIACSCEG SQFKLFDPNL GEFQSSRSAA 240
PQLIKGLIDH YNSLNYDVAC VNEFRVS 267
|
FASTA
(Canonical) |
>LipidDB-319-00189|Q52430
MKIGTQATSLAVLHNQESHAPQAPIAVRPEPAHAIPEIPLDLAIRPRTRGIHPFLAMTLG
DKGCASSSGVSLEDDSHTQVSLSDFSVASRDVNHNNICAGLSTEWLVMSSDGDAESRMDH
LDYNGEGQSRGSERHQVYNDALRAALSNDDEAPFFTASTAVIEDAGFSLRREPKTVHASG
GSAQLGQTVAHDVAQSGRKHLLSLRFANVQGHAIACSCEGSQFKLFDPNLGEFQSSRSAA
PQLIKGLIDHYNSLNYDVACVNEFRVS
|
Gene Ontology |
GO:0033644; C:host cell membrane; IEA:UniProtKB-KW GO:0016020; C:membrane; IEA:UniProtKB-KW GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW GO:0009405; P:pathogenesis; IEA:UniProtKB-KW |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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