| Tag |
Content |
LipidDB ID |
LipidDB-10498-00296 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
6.24 |
Molecular Weight |
281481.62 |
Genbank Protein ID |
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Genbank Nucleotide ID |
|
Protein Name |
p150 |
Protein Synonyms/Alias |
220 kDa polyprotein; |
Gene Name |
|
Gene Synonyms/Alias |
Ba71V-92; CP2475L; |
Created Date |
30-AUG-2005 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
2 | Canonical | ******MGNRGSSTS | [1] | N-Myristoylation |
|
Organism |
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V (ASFV) |
NCBI Taxa ID |
10498 |
Reference |
[1] Simón-Mateo C, Andrés G, Viñuela E. Polyprotein processing in African swinefever virus: a novel gene expression strategy for a DNA virus. EMBO J. 1993Jul;12(7):2977-87.[ PMID:8335009]
|
Functional Description |
Polyprotein pp220 is essential for the core assembly. Its myristoyl moiety may function as a membrane-anchoring signal to bind the developing core shell to the inner viral envelope.The structural protein p14 is a component of the virus core shell.The structural protein p150 is a component of the virus core shell. |
Sequence Annotation |
Functional site: 45 46 Cleavage; by viral protease S273R.
Functional site: 369 370 Cleavage; by viral protease S273R.
Functional site: 523 524 Cleavage; by viral protease S273R.
Functional site: 894 895 Cleavage; by viral protease S273R.
|
Protein Length |
2475 AA. |
Protein Sequence
(Canonical) |
MGNRGSSTSS RPPLSSEANL YAKLQDHIQR QTRPFSGGGY FNGGGDKNPV QHIKDYHIDS 60
VSSKAKLRVI EGIIRAIAKI GFKVDTKQPI EDILKDIKKQ LPDPRAGSTF VKNAEKQETV 120
CKMIADAINQ EFIDLGQDKL IDTTDGAASI CRQIVLYINS LTHGLRAEYL DVHGSIENTL 180
ENIKLLNDAI KQLHERMVTE VTKAAPNEEV INAVTMIEAV YRRLLNEQNL QINILTNFID 240
NILTPTQKEL DKLQTDEVDI IKLLNDTNSV LGTKNFGKVL SYTLCNLGIA ASVANKINKA 300
LQKVGLKVEQ YLQSKNWAEF DKELDLKRFS GLVSAENIAE FEKAVNLLRQ TFNERHKILE 360
NSCAKKGGDE EKTPLDRRIE AQRLDRKHIL MEFLNKSTQA YNDFLENVKK IGIKLVKEIA 420
LTPNITRLRD ALSRINDMGT IALDLSLIGF YTNAAAREER ETFLTQFMLV KNVLEEQSKI 480
DPNFKNLYDS CSRLLQIIDF YTDIVQKKYG GGEDCECTRV GGAALTVEEL GLSKAARSQV 540
DLNQAINTFM YYYYVAQIYS NLTHNKQEFQ SYEENYATIL GDAIAGRLMQ LDTEKNARIN 600
SPAVDLARGH VGPNPGGAQE ADWKAAVSAI ELEYDVKRRF YRALEGLDLY LKNITKTFVN 660
NIDSIQTVQQ MLDGVRIIGR WFTEATGDTL AQVFESFPTS AGNDSNVFTD NAPAGHYYEK 720
VAAEIQQGRS VGTLRPVRAS QAKNIRDLIG RSLSNFQALK NIINAFARIG DMLGGEELRQ 780
MVPMSPLQIY KTLLEYIQHS ALSVGLKNLN QSEIGGQRVA LARTPEEAAQ RVYLSTVRVN 840
DALSTRWETE DVFFTFMLKS MAAKIFIVLG IYDMFERPEP VYKLIPTRMI LGGADELEPE 900
VIPEAAELYF RLPRLAEFYQ KLFSFRDENV QISMLPELEG IFSGLIRIIF MRPIELINIG 960
DYSETEIRQL IKEINVIYQH FNLEYGEQEA TKKALIHFVN EINRRFGVIT RTEWEKFQRI 1020
VQEARTMNDF GMMNQTNYSI LPDEDGYTQS SQLLPSDRFI SPSTQPTPKW RPALYNIDSV 1080
DVQTGMLQPN SQWDLVQKFR KQLSEMFEDP SLQQELGKVS YQELIRQAIN ELKKEHTDKI 1140
QIVSKLIQGS ESLADTDVNK IFLFHETVIT GLNLLSAIYV LLNNFRNNIK GLDLDTIQKS 1200
IIEWLRETQA ANVNRANLID WLGRKHGAIS EIRNPGLVVK ENDVRLSRVY PDPTTNATAP 1260
QDQNLVTETL FAWIVPYVGI PAGGGVRAEQ ELAARYLVDN QRIMQLLLTN IFEMTSSFNK 1320
MVQVRFPETS TAQVHLDFTG LISLIDSLMA DTKYFLNLLR PHIDKNIIQY YENRSNPGSF 1380
YWLEEHLIDK LIKPPTDAGG RPLPGGELGL EGVNQIINKT YILLTKPYNV LQLRGGVQRR 1440
DAANIQINNN PQPSERFEQY GRVFSRLVFY DALENNSGLR VEQVVLGDFR LSNLIRTNNA 1500
QEENTLSYWD NMAPRTYANV NDAANNLRRY RLYGSDYGIQ NNRSMMMVFN QLVASYIARF 1560
YDAPSGKIYL NLINAFANGN FSQAVMELGY THPDLARDNI AFGHRGDPTE QSVLLLSLGL 1620
MLQRLIKDTN RQGLSQHLIS TLTEIPIYLK ENYRANLPLF NKMFNILISQ GELLKQFIQY 1680
TNVQLARPNL MGLLGANNDS VIYYNNNINV PMTGLSVGQA ALRGIGGVFR PNVTLMPLGD 1740
AQNNTSDVVR KRLVAVIDGI IRGSHTLADS AMEVLHELTD HPIYLETEEH FIQNYMSRYN 1800
KEPLMPFSLS LYYLRDLRIE NNEVYDPLLY PNLESGSPEF KLLYGTRKLL GNDPVQLSDM 1860
PGVQLIMKNY NETVVAREQI TPTRFEHFYT HAIQALRFIV NIRSFKTVMM YNENTFGGVN 1920
LISENRDDKP IITAGIGMNA VYSLRKTLQD VISFVESSYQ EEQINHIHKI VSPKGQTRTL 1980
GSNRERERIF NLFDMNIIPI NVNALMRSIP LANIYNYDYS FEEIACLMYG ISAEKVRSLN 2040
TAAPQPDIAE VLNIPNRPPM NTREFMLKLL INPYVSVSIT QYGNELMSKG SAGYMSRIFR 2100
GDNALNMGRP KFLSDQIFNK VLFGSLYPTQ FDYDEAGPGL AAGIQRGREQ WGQPLSEYIN 2160
QALHELVRTI RIPQKLRVLR NIIVKNQLIA DLTTIREQLV SMRREVENMI QTPEIQNNPT 2220
PEVIAAAQNW TQQYRARVDT LINFIGNIGQ PNSMLDLIQT ITPVTVRAQL GVIFNRHGIP 2280
VPHPRQILQT DDEATQWFMT NILNIPAIIM TPFTDLANDL RTFLETLERY VFNVPRWLGP 2340
STGRVARAPV RMAPRDMRHP ISYTENSVLT YITEQNREEG PWSIVKQVGV GIQKPTLVQI 2400
GKDRFDTRLI RNLIFITNIQ RLLRLRLNLE LSQFRNVLVS PDHIINPSIT EYGFSITGPS 2460
ETFSDKQYDS DIRIL 2475
|
FASTA
(Canonical) |
>LipidDB-10498-00296|Q08358
MGNRGSSTSSRPPLSSEANLYAKLQDHIQRQTRPFSGGGYFNGGGDKNPVQHIKDYHIDS
VSSKAKLRVIEGIIRAIAKIGFKVDTKQPIEDILKDIKKQLPDPRAGSTFVKNAEKQETV
CKMIADAINQEFIDLGQDKLIDTTDGAASICRQIVLYINSLTHGLRAEYLDVHGSIENTL
ENIKLLNDAIKQLHERMVTEVTKAAPNEEVINAVTMIEAVYRRLLNEQNLQINILTNFID
NILTPTQKELDKLQTDEVDIIKLLNDTNSVLGTKNFGKVLSYTLCNLGIAASVANKINKA
LQKVGLKVEQYLQSKNWAEFDKELDLKRFSGLVSAENIAEFEKAVNLLRQTFNERHKILE
NSCAKKGGDEEKTPLDRRIEAQRLDRKHILMEFLNKSTQAYNDFLENVKKIGIKLVKEIA
LTPNITRLRDALSRINDMGTIALDLSLIGFYTNAAAREERETFLTQFMLVKNVLEEQSKI
DPNFKNLYDSCSRLLQIIDFYTDIVQKKYGGGEDCECTRVGGAALTVEELGLSKAARSQV
DLNQAINTFMYYYYVAQIYSNLTHNKQEFQSYEENYATILGDAIAGRLMQLDTEKNARIN
SPAVDLARGHVGPNPGGAQEADWKAAVSAIELEYDVKRRFYRALEGLDLYLKNITKTFVN
NIDSIQTVQQMLDGVRIIGRWFTEATGDTLAQVFESFPTSAGNDSNVFTDNAPAGHYYEK
VAAEIQQGRSVGTLRPVRASQAKNIRDLIGRSLSNFQALKNIINAFARIGDMLGGEELRQ
MVPMSPLQIYKTLLEYIQHSALSVGLKNLNQSEIGGQRVALARTPEEAAQRVYLSTVRVN
DALSTRWETEDVFFTFMLKSMAAKIFIVLGIYDMFERPEPVYKLIPTRMILGGADELEPE
VIPEAAELYFRLPRLAEFYQKLFSFRDENVQISMLPELEGIFSGLIRIIFMRPIELINIG
DYSETEIRQLIKEINVIYQHFNLEYGEQEATKKALIHFVNEINRRFGVITRTEWEKFQRI
VQEARTMNDFGMMNQTNYSILPDEDGYTQSSQLLPSDRFISPSTQPTPKWRPALYNIDSV
DVQTGMLQPNSQWDLVQKFRKQLSEMFEDPSLQQELGKVSYQELIRQAINELKKEHTDKI
QIVSKLIQGSESLADTDVNKIFLFHETVITGLNLLSAIYVLLNNFRNNIKGLDLDTIQKS
IIEWLRETQAANVNRANLIDWLGRKHGAISEIRNPGLVVKENDVRLSRVYPDPTTNATAP
QDQNLVTETLFAWIVPYVGIPAGGGVRAEQELAARYLVDNQRIMQLLLTNIFEMTSSFNK
MVQVRFPETSTAQVHLDFTGLISLIDSLMADTKYFLNLLRPHIDKNIIQYYENRSNPGSF
YWLEEHLIDKLIKPPTDAGGRPLPGGELGLEGVNQIINKTYILLTKPYNVLQLRGGVQRR
DAANIQINNNPQPSERFEQYGRVFSRLVFYDALENNSGLRVEQVVLGDFRLSNLIRTNNA
QEENTLSYWDNMAPRTYANVNDAANNLRRYRLYGSDYGIQNNRSMMMVFNQLVASYIARF
YDAPSGKIYLNLINAFANGNFSQAVMELGYTHPDLARDNIAFGHRGDPTEQSVLLLSLGL
MLQRLIKDTNRQGLSQHLISTLTEIPIYLKENYRANLPLFNKMFNILISQGELLKQFIQY
TNVQLARPNLMGLLGANNDSVIYYNNNINVPMTGLSVGQAALRGIGGVFRPNVTLMPLGD
AQNNTSDVVRKRLVAVIDGIIRGSHTLADSAMEVLHELTDHPIYLETEEHFIQNYMSRYN
KEPLMPFSLSLYYLRDLRIENNEVYDPLLYPNLESGSPEFKLLYGTRKLLGNDPVQLSDM
PGVQLIMKNYNETVVAREQITPTRFEHFYTHAIQALRFIVNIRSFKTVMMYNENTFGGVN
LISENRDDKPIITAGIGMNAVYSLRKTLQDVISFVESSYQEEQINHIHKIVSPKGQTRTL
GSNRERERIFNLFDMNIIPINVNALMRSIPLANIYNYDYSFEEIACLMYGISAEKVRSLN
TAAPQPDIAEVLNIPNRPPMNTREFMLKLLINPYVSVSITQYGNELMSKGSAGYMSRIFR
GDNALNMGRPKFLSDQIFNKVLFGSLYPTQFDYDEAGPGLAAGIQRGREQWGQPLSEYIN
QALHELVRTIRIPQKLRVLRNIIVKNQLIADLTTIREQLVSMRREVENMIQTPEIQNNPT
PEVIAAAQNWTQQYRARVDTLINFIGNIGQPNSMLDLIQTITPVTVRAQLGVIFNRHGIP
VPHPRQILQTDDEATQWFMTNILNIPAIIMTPFTDLANDLRTFLETLERYVFNVPRWLGP
STGRVARAPVRMAPRDMRHPISYTENSVLTYITEQNREEGPWSIVKQVGVGIQKPTLVQI
GKDRFDTRLIRNLIFITNIQRLLRLRLNLELSQFRNVLVSPDHIINPSITEYGFSITGPS
ETFSDKQYDSDIRIL
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Gene Ontology |
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Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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