LipidDB-10299-00849

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-10299-00849

Entry Name

TEG2_HHV11

UniProt Accession

P04289; B9VQD8; Q09IC2;

Theoretical PI

5.2

Molecular Weight

10486.62

Genbank Protein ID

CAA32347.1; CAA27452.1; ABI63473.1; ACM62233.1;

Genbank Nucleotide ID

X14112; X03839; DQ889502; FJ593289;

Protein Name

Tegument protein UL11

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

UL11;

Created Date

20-MAR-1987

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
2	Canonical	******MGLSFSGAR	[2]	N-Myristoylation
11	Canonical	SFSGARPCCCRNNVL	[1]	S-Palmitoylation
12	Canonical	FSGARPCCCRNNVLI	[1]	S-Palmitoylation
13	Canonical	SGARPCCCRNNVLIT	[1]	S-Palmitoylation

Organism

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex viru 1)

NCBI Taxa ID

10299

Reference

[1] Koshizuka T, Kawaguchi Y, Nozawa N, Mori I, Nishiyama Y. Herpes simplex virus protein UL11 but not UL51 is associated with lipid rafts. Virus Genes. 2007Dec;35(3):571-5. Epub 2007 Aug 13.[PMID:17694428]
[2] MacLean CA, Dolan A, Jamieson FE, McGeoch DJ. The myristylated virion proteinsof herpes simplex virus type 1: investigation of their role in the virus lifecycle. J Gen Virol. 1992 Mar;73 ( Pt 3):539-47.[PMID:1312117]

Functional Description

Tegument protein that may play a role in the nucleocapsid secondary envelopment at the trans-Golgi network during virus morphogenesis.

Sequence Annotation

Region: 37 43 Asp/Glu-rich (acidic).
Motif: 18 19 Di-leucine-like internalization motif.
Modified residue: 40 40 Phosphoserine.

Protein Length

96 AA.

Protein Sequence
(Canonical)

MGLSFSGARP CCCRNNVLIT DDGEVVSLTA HDFDVVDIES EEEGNFYVPP DMRGVTRAPG  60
RQRLRSSDPP SRHTHRRTPG GACPATQFPP PMSDSE                            96
MGLSFSGARP CCCRNNVLIT DDGEVVSLTA HDFDVVDIES EEEGNFYVPP DMRGVTRAPG  60
RQRLRSSDPP SRHTHRRTPG GACPATQFPP PMSDSE                            96

FASTA
(Canonical)

>LipidDB-10299-00849|P04289
MGLSFSGARPCCCRNNVLITDDGEVVSLTAHDFDVVDIESEEEGNFYVPPDMRGVTRAPG
RQRLRSSDPPSRHTHRRTPGGACPATQFPPPMSDSE
MGLSFSGARPCCCRNNVLITDDGEVVSLTAHDFDVVDIESEEEGNFYVPPDMRGVTRAPG
RQRLRSSDPPSRHTHRRTPGGACPATQFPPPMSDSE

Gene Ontology

GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-KW
GO:0042025; C:host cell nucleus; IEA:UniProtKB-KW
GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-KW
GO:0016020; C:membrane; IEA:UniProtKB-KW
GO:0019033; C:viral tegument; IEA:UniProtKB-KW
GO:0009653; P:anatomical structure morphogenesis; IEA:InterPro

Interpro

InterPro; IPR024351; Tegument_UL11_Herpesvir
InterPro; IPR016395; UL11_simplexvir-type

Pfam

Pfam; PF11094; UL11;

SMART

PROSITE

PRINTS