| Tag |
Content |
LipidDB ID |
LipidDB-10249-00848 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
8.74 |
Molecular Weight |
43561.71 |
Genbank Protein ID |
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Genbank Nucleotide ID |
|
Protein Name |
Virion membrane protein A16 |
Protein Synonyms/Alias |
|
Gene Name |
|
Gene Synonyms/Alias |
A16L; |
Created Date |
01-FEB-1991 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
2 | Canonical | ******MGAAVTLNR | [1] | N-Myristoylation |
|
Organism |
Vaccinia virus (strain Copenhagen) (VACV) |
NCBI Taxa ID |
10249 |
Reference |
[1] Martin KH, Grosenbach DW, Franke CA, Hruby DE. Identification and analysis of three myristylated vaccinia virus late proteins. J Virol. 1997 Jul;71(7):5218-26.[ PMID:9188589]
|
Functional Description |
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation) (By similarity). |
Sequence Annotation |
Topological domain: 2 342 Virion surface.
Transmembrane: 343 363 Helical; Signal-anchor for type IImembrane protein.
Topological domain: 364 378 Intravirion.
|
Protein Length |
378 AA. |
Protein Sequence
(Canonical) |
MGAAVTLNRI KIAPGIADIR DKYMELGFNY PEYNRAVKFA EESYTYYYET SPGEIKPKFC 60
LIDGMSIDHC SSFIVPEFAK QYVLIHGEPC SSFKFRPGSL IYYQNEVTPE YIKDLKHATD 120
YIASGQRCHF IKKDYLLGDS DSVAKCCSKT NTKHCPKIFN NNYKTEHCDD FMTGFCRNDP 180
GNPNCLEWLR AKRKPAMSTY SDICSKHMDA RYCSEFIRII RPDYFTFGDT ALYVFCNDHK 240
GNRNCWCANY PKSNSGDKYL GPRVCWLHEC TDESRDRKWL YYNQDVQRTR CKYVGCTINV 300
NSLALKNSQA ELTSNCTRTT SAVGDVHHPG EPVVKDKIKL PTWLGAAITL VVISVIFYFI 360
SIYSRPKIKT NDINVRRR 378
|
FASTA
(Canonical) |
>LipidDB-10249-00848|P20993
MGAAVTLNRIKIAPGIADIRDKYMELGFNYPEYNRAVKFAEESYTYYYETSPGEIKPKFC
LIDGMSIDHCSSFIVPEFAKQYVLIHGEPCSSFKFRPGSLIYYQNEVTPEYIKDLKHATD
YIASGQRCHFIKKDYLLGDSDSVAKCCSKTNTKHCPKIFNNNYKTEHCDDFMTGFCRNDP
GNPNCLEWLRAKRKPAMSTYSDICSKHMDARYCSEFIRIIRPDYFTFGDTALYVFCNDHK
GNRNCWCANYPKSNSGDKYLGPRVCWLHECTDESRDRKWLYYNQDVQRTRCKYVGCTINV
NSLALKNSQAELTSNCTRTTSAVGDVHHPGEPVVKDKIKLPTWLGAAITLVVISVIFYFI
SIYSRPKIKTNDINVRRR
|
Gene Ontology |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0019031; C:viral envelope; IEA:UniProtKB-KW GO:0039663; P:membrane fusion involved in viral entry into host cell; IEA:UniProtKB-KW |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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