| Tag |
Content |
LipidDB ID |
LipidDB-10116-00385 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
8.56 |
Molecular Weight |
33412.23 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Sodium/potassium-transporting ATPase subunit beta-2 |
Protein Synonyms/Alias |
Sodium/potassium-dependent ATPase subunit beta-2; |
Gene Name |
Atp1b2 |
Gene Synonyms/Alias |
|
Created Date |
01-JAN-1990 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
10 | Canonical | IQKEKKSCGQVVEEW | [1] | S-Palmitoylation |
|
Organism |
Rattus norvegicus (Rat) |
NCBI Taxa ID |
10116 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. |
Sequence Annotation |
Topological domain: 1 39 Cytoplasmic.
Transmembrane: 40 67 Helical; Signal-anchor for type IImembrane protein.
Topological domain: 68 290 Extracellular.
Region: 193 290 immunoglobulin-like.
|
Protein Length |
290 AA. |
Protein Sequence
(Canonical) |
MVIQKEKKSC GQVVEEWKEF VWNPRTHQFM GRTGTSWAFI LLFYLVFYGF LTAMFTLTMW 60
VMLQTVSDHT PKYQDRLATP GLMIRPKTEN LDVIVNISDT ESWDQHVQKL NKFLEPYNDS 120
IQAQKNDVCR PGRYYEQPDN GVLNYPKRAC QFNRTQLGNC SGIGDPTHYG YSTGQPCVFI 180
KMNRVINFYA GANQSMNVTC VGKKDEDAEN LGHFIMFPAN GNIDLMYFPY YGKKFHVNYT 240
QPLVAVKFLN VTPNVEVNVE CRINAANIAT DDERDKFAAR VAFKLRINKA 290
|
FASTA
(Canonical) |
>LipidDB-10116-00385|P13638
MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNISDTESWDQHVQKLNKFLEPYNDS
IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDPTHYGYSTGQPCVFI
KMNRVINFYAGANQSMNVTCVGKKDEDAENLGHFIMFPANGNIDLMYFPYYGKKFHVNYT
QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAARVAFKLRINKA
|
Gene Ontology |
GO:0016324; C:apical plasma membrane; IDA:RGD GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro GO:0005391; F:sodium:potassium-exchanging ATPase activity; IDA:RGD GO:0007155; P:cell adhesion; IEA:UniProtKB-KW GO:0035725; P:sodium ion transmembrane transport; IDA:GOC |
Interpro |
|
Pfam |
|
SMART |
|
PROSITE |
PROSITE; PS00390; ATPASE_NA_K_BETA_1; PROSITE; PS00391; ATPASE_NA_K_BETA_2; |
PRINTS |
|