| Tag |
Content |
LipidDB ID |
LipidDB-10116-00264 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
4.91 |
Molecular Weight |
54090.96 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Lysosome membrane protein 2 |
Protein Synonyms/Alias |
85 kDa lysosomal membrane sialoglycoprotein; LGP85; CD36 antigen-like 2; Lysosome membrane protein II; LIMP II; Scavenger receptor class B member 2; CD36; |
Gene Name |
Scarb2 |
Gene Synonyms/Alias |
Cd36l2; Limpii; |
Created Date |
01-AUG-1992 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
4 | Canonical | ****MARCCFYTAGT | [1] | S-Palmitoylation | 5 | Canonical | ***MARCCFYTAGTL | [1] | S-Palmitoylation | 458 | Canonical | LIFTWLACRGQGSTD | [1] | S-Palmitoylation |
|
Organism |
Rattus norvegicus (Rat) |
NCBI Taxa ID |
10116 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. |
Sequence Annotation |
Topological domain: 2 4 Cytoplasmic.
Transmembrane: 5 27 Helical.
Topological domain: 28 433 Lumenal.
Transmembrane: 434 459 Helical.
Topological domain: 460 478 Cytoplasmic.
Region: 155 191 Important for interaction with GBA.
|
Protein Length |
478 AA. |
Protein Sequence
(Canonical) |
MARCCFYTAG TLSLLLLVTS VTLLVARVFQ KAVDQTIEKN MVLQNGTKVF DSWEKPPLPV 60
YIQFYFFNVT NPEEILQGEI PLLEEVGPYT YRELRNKANV QFGENGTTIS AVTNKAYIFE 120
RNQSVGDPTV DLIRTINIPL LTVVEMAQQP FLREIIEAML KAYQQTLFVT HTVHELLWGY 180
KDEVLSLVHI FRPDVSPNFG LFYERNGTND GEYVFLTGED NYLNFTKIVE WNGKTSLDWW 240
TTDTCNMING TDGDSFHPLI SKDETLYIFP SDFCRSVYIT FSSFENVEGL PAFRYKVPAE 300
ILANSSENAG FCIPEGNCMD AGVLNVSICK NGAPIIMSFP HFYQADEKFV SAIKGMRPNK 360
EEHESFVDIN PLTGIILRGA KRFQINTYVK KLDDFVETGN IRTMVFPVMY LNESVLIDKE 420
TASQLKSVIN TTLIVTNIPY IIMALGVFFG LIFTWLACRG QGSTDEGTAD ERAPLIRT 478
|
FASTA
(Canonical) |
>LipidDB-10116-00264|P27615
MARCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFDSWEKPPLPV
YIQFYFFNVTNPEEILQGEIPLLEEVGPYTYRELRNKANVQFGENGTTISAVTNKAYIFE
RNQSVGDPTVDLIRTINIPLLTVVEMAQQPFLREIIEAMLKAYQQTLFVTHTVHELLWGY
KDEVLSLVHIFRPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFTKIVEWNGKTSLDWW
TTDTCNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFENVEGLPAFRYKVPAE
ILANSSENAGFCIPEGNCMDAGVLNVSICKNGAPIIMSFPHFYQADEKFVSAIKGMRPNK
EEHESFVDINPLTGIILRGAKRFQINTYVKKLDDFVETGNIRTMVFPVMYLNESVLIDKE
TASQLKSVINTTLIVTNIPYIIMALGVFFGLIFTWLACRGQGSTDEGTADERAPLIRT
|
Gene Ontology |
GO:0070062; C:extracellular vesicular exosome; IEA:Ensembl GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0043202; C:lysosomal lumen; IEA:Ensembl GO:0005765; C:lysosomal membrane; ISS:UniProtKB GO:0004872; F:receptor activity; IEA:InterPro GO:0007155; P:cell adhesion; IEA:InterPro GO:0006622; P:protein targeting to lysosome; IEA:Ensembl |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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