| Tag |
Content |
LipidDB ID |
LipidDB-10090-01379 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.7 |
Molecular Weight |
37064.36 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Embigin |
Protein Synonyms/Alias |
Teratocarcinoma glycoprotein Gp-70; |
Gene Name |
Emb |
Gene Synonyms/Alias |
Gp70; |
Created Date |
01-AUG-1991 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
184 | Canonical | STVLKCVCQDCLPLN | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Plays a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity). Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. |
Sequence Annotation |
Topological domain: 34 254 Extracellular.
Transmembrane: 255 283 Helical.
Topological domain: 284 330 Cytoplasmic.
Domain: 38 161 Ig-like V-type 1.
Domain: 162 256 Ig-like V-type 2.
|
Protein Length |
330 AA. |
Protein Sequence
(Canonical) |
MRSHTGLRAL VAPGYPLLLL CLLAATRPDP AEGDPTDPTF TSLPVREEMM AKYSNLSLKS 60
CNISVTEKSN VSVEENVILE KPSHVELKCV YTATKDLNLM NVTWKKDDEP LETTGDFNTT 120
KMGNTLTSQY RFIVFNSKQL GKYSCVFGEK ELRGTFNIHV PKAHGKKKSL IAYVGDSTVL 180
KCVCQDCLPL NWTWYMGNET AQVPIDAHSN EKYIINGSHA NETRLKIKHL LEEDGGSYWC 240
RATFQLGESE EQNELVVLSF LVPLKPFLAI LAEVILLVAI ILLCEVYTHK KKNDPDAGKE 300
FEQIEQLKSD DSNGIENNVP RYRKTDSADQ 330
|
FASTA
(Canonical) |
>LipidDB-10090-01379|P21995
MRSHTGLRALVAPGYPLLLLCLLAATRPDPAEGDPTDPTFTSLPVREEMMAKYSNLSLKS
CNISVTEKSNVSVEENVILEKPSHVELKCVYTATKDLNLMNVTWKKDDEPLETTGDFNTT
KMGNTLTSQYRFIVFNSKQLGKYSCVFGEKELRGTFNIHVPKAHGKKKSLIAYVGDSTVL
KCVCQDCLPLNWTWYMGNETAQVPIDAHSNEKYIINGSHANETRLKIKHLLEEDGGSYWC
RATFQLGESEEQNELVVLSFLVPLKPFLAILAEVILLVAIILLCEVYTHKKKNDPDAGKE
FEQIEQLKSDDSNGIENNVPRYRKTDSADQ
|
Gene Ontology |
GO:0030054; C:cell junction; IEA:UniProtKB-KW GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB GO:0045202; C:synapse; IEA:UniProtKB-KW GO:0097159; F:organic cyclic compound binding; IEA:Ensembl GO:0007155; P:cell adhesion; IEA:Ensembl GO:0035879; P:plasma membrane lactate transport; ISS:UniProtKB |
Interpro |
|
Pfam |
|
SMART |
|
PROSITE |
|
PRINTS |
|