LipidDB ID

LipidDB-10090-01378

Entry Name

UniProt Accession

P08556;

Theoretical PI

5.01

Molecular Weight

21199.08

Genbank Protein ID

AAA39839.1; AAA39839.1; AAA39839.1; AAA39839.1; CAA31958.1; CAA30010.1;

Genbank Nucleotide ID

M12124; M12121; M12122; M12123; X13664; X06909;

Protein Name

GTPase NRas

Protein Synonyms/Alias

Transforming protein N-Ras;

Gene Name

Nras

Gene Synonyms/Alias

Created Date

01-AUG-1988

Organism

Mus musculus (Mouse)

NCBI Taxa ID

10090

Reference

[1] Predicted from GPS-Lipid

Functional Description

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Sequence Annotation

Nucleotide-binding: 10 17 GTP.
Nucleotide-binding: 57 61 GTP.
Nucleotide-binding: 116 119 GTP.
Region: 166 185 Hypervariable region.
Motif: 32 40 Effector region.
Modified residue: 186 186 Cysteine methyl ester.

Protein Length

189 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW
GO:0016020; C:membrane; IDA:MGI
GO:0005886; C:plasma membrane; TAS:Reactome
GO:0005525; F:GTP binding; IEA:UniProtKB-KW
GO:0003924; F:GTPase activity; TAS:MGI
GO:0032403; F:protein complex binding; ISO:MGI
GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:MGI
GO:0007265; P:Ras protein signal transduction; TAS:MGI
GO:0051726; P:regulation of cell cycle; TAS:MGI

Interpro

InterPro; IPR027417; P-loop_NTPase
InterPro; IPR005225; Small_GTP-bd_dom
InterPro; IPR001806; Small_GTPase
InterPro; IPR020849; Small_GTPase_Ras

Pfam

Pfam; PF00071; Ras;

SMART

SMART; SM00173; RAS;

PROSITE

PROSITE; PS51421; RAS;

PRINTS

PRINTS; PR00449; RASTRNSFRMNG;