| Tag |
Content |
LipidDB ID |
LipidDB-10090-01330 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
8.46 |
Molecular Weight |
14666.95 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Interferon-induced transmembrane protein 5 |
Protein Synonyms/Alias |
Bone-restricted interferon-induced transmembrane protein-like protein; Bril; Dispanin subfamily A member 1; DSPA1; Fragilis family member 4; |
Gene Name |
Ifitm5 |
Gene Synonyms/Alias |
Bril; Fragilis4; |
Created Date |
05-OCT-2010 |
| Lipid Modification Sites |
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
52 | Canonical | STMYLNLCCLGFLAL | [1] | S-Palmitoylation | 53 | Canonical | TMYLNLCCLGFLALV | [1] | S-Palmitoylation | 86 | Canonical | QYGSKAKCYNILAAM | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Tsukamoto T, Li X, Morita H, Minowa T, Aizawa T, Hanagata N, Demura M. Role ofS-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells.PLoS One. 2013 Sep 18;8(9):e75831. doi: 10.1371/journal.pone.0075831. eCollection2013.[ PMID:24058703]
|
Functional Description |
Plays a role in bone mineralization. |
Sequence Annotation |
Topological domain: 1 39 Extracellular. Transmembrane: 40 60 Helical. Topological domain: 61 88 Cytoplasmic. Transmembrane: 89 109 Helical. Topological domain: 110 134 Extracellular.
|
Protein Length |
134 AA. |
Protein Sequence (Canonical) |
MDTSYPREDP RAPSSRKADA AAHTALSMGT PGPTPRDHML WSVFSTMYLN LCCLGFLALV 60
HSVKARDQKM AGNLEAARQY GSKAKCYNIL AAMWTLVPPL LLLGLVVTGA LHLSKLAKDS 120
AAFFSTKFDE EDYN 134
|
FASTA (Canonical) |
>LipidDB-10090-01330|O88728
MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALV
HSVKARDQKMAGNLEAARQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSKLAKDS
AAFFSTKFDEEDYN
|
Gene Ontology |
GO:0016021; C:integral component of membrane; TAS:MGI GO:0005886; C:plasma membrane; IDA:MGI GO:0030282; P:bone mineralization; IMP:MGI GO:0007275; P:multicellular organismal development; TAS:MGI GO:0030500; P:regulation of bone mineralization; IEA:UniProtKB-KW GO:0009607; P:response to biotic stimulus; IEA:InterPro |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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