| Tag |
Content |
LipidDB ID |
LipidDB-10090-01270 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
6.82 |
Molecular Weight |
67091.97 |
Genbank Protein ID |
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Genbank Nucleotide ID |
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Protein Name |
High affinity cationic amino acid transporter 1 |
Protein Synonyms/Alias |
CAT-1; CAT1; Ecotropic retroviral leukemia receptor; Ecotropic retrovirus receptor; ERR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter; |
Gene Name |
Slc7a1 |
Gene Synonyms/Alias |
Atrc1; Rec-1; |
Created Date |
01-OCT-1996 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
3 | Canonical | *****MGCKNLLGLG | [1] | S-Palmitoylation | 21 | Canonical | LRRKVVDCSREESRL | [1] | S-Palmitoylation | 31 | Canonical | EESRLSRCLNTYDLV | [1] | S-Palmitoylation | 621 | Canonical | PDSNLDQCK****** | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. |
Sequence Annotation |
Topological domain: 1 35 Cytoplasmic.
Transmembrane: 36 57 Helical.
Topological domain: 58 61 Extracellular.
Transmembrane: 62 82 Helical.
Topological domain: 83 102 Cytoplasmic.
Transmembrane: 103 123 Helical.
Topological domain: 124 162 Extracellular.
Transmembrane: 163 183 Helical.
Topological domain: 184 191 Cytoplasmic.
Transmembrane: 192 212 Helical.
Topological domain: 213 239 Extracellular.
Transmembrane: 240 260 Helical.
Topological domain: 261 280 Cytoplasmic.
Transmembrane: 281 300 Helical.
Topological domain: 301 330 Extracellular.
Transmembrane: 331 351 Helical.
Topological domain: 352 377 Cytoplasmic.
Transmembrane: 378 398 Helical.
Topological domain: 399 401 Extracellular.
Transmembrane: 402 422 Helical.
Topological domain: 423 485 Cytoplasmic.
Transmembrane: 486 506 Helical.
Topological domain: 507 519 Extracellular.
Transmembrane: 520 544 Helical.
Topological domain: 545 552 Cytoplasmic.
Transmembrane: 553 573 Helical.
Topological domain: 574 577 Extracellular.
Transmembrane: 578 598 Helical.
Topological domain: 599 622 Cytoplasmic.
|
Protein Length |
622 AA. |
Protein Sequence
(Canonical) |
MGCKNLLGLG QQMLRRKVVD CSREESRLSR CLNTYDLVAL GVGSTLGAGV YVLAGAVARE 60
NAGPAIVISF LIAALASVLA GLCYGEFGAR VPKTGSAYLY SYVTVGELWA FITGWNLILS 120
YIIGTSSVAR AWSATFDELI GKPIGEFSRQ HMALNAPGVL AQTPDIFAVI IIIILTGLLT 180
LGVKESAMVN KIFTCINVLV LCFIVVSGFV KGSIKNWQLT EKNFSCNNND TNVKYGEGGF 240
MPFGFSGVLS GAATCFYAFV GFDCIATTGE EVKNPQKAIP VGIVASLLIC FIAYFGVSAA 300
LTLMMPYFCL DIDSPLPGAF KHQGWEEAKY AVAIGSLCAL STSLLGSMFP MPRVIYAMAE 360
DGLLFKFLAK INNRTKTPVI ATVTSGAIAA VMAFLFELKD LVDLMSIGTL LAYSLVAACV 420
LVLRYQPEQP NLVYQMARTT EELDRVDQNE LVSASESQTG FLPVAEKFSL KSILSPKNVE 480
PSKFSGLIVN ISAGLLAALI ITVCIVAVLG REALAEGTLW AVFVMTGSVL LCMLVTGIIW 540
RQPESKTKLS FKVPFVPVLP VLSIFVNIYL MMQLDQGTWV RFAVWMLIGF TIYFGYGIWH 600
SEEASLAAGQ AKTPDSNLDQ CK 622
|
FASTA
(Canonical) |
>LipidDB-10090-01270|Q09143
MGCKNLLGLGQQMLRRKVVDCSREESRLSRCLNTYDLVALGVGSTLGAGVYVLAGAVARE
NAGPAIVISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILS
YIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVLAQTPDIFAVIIIIILTGLLT
LGVKESAMVNKIFTCINVLVLCFIVVSGFVKGSIKNWQLTEKNFSCNNNDTNVKYGEGGF
MPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAA
LTLMMPYFCLDIDSPLPGAFKHQGWEEAKYAVAIGSLCALSTSLLGSMFPMPRVIYAMAE
DGLLFKFLAKINNRTKTPVIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLVAACV
LVLRYQPEQPNLVYQMARTTEELDRVDQNELVSASESQTGFLPVAEKFSLKSILSPKNVE
PSKFSGLIVNISAGLLAALIITVCIVAVLGREALAEGTLWAVFVMTGSVLLCMLVTGIIW
RQPESKTKLSFKVPFVPVLPVLSIFVNIYLMMQLDQGTWVRFAVWMLIGFTIYFGYGIWH
SEEASLAAGQAKTPDSNLDQCK
|
Gene Ontology |
GO:0016021; C:integral component of membrane; IC:MGI GO:0015181; F:arginine transmembrane transporter activity; IDA:MGI GO:0015809; P:arginine transport; IDA:MGI |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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