| Tag |
Content |
LipidDB ID |
LipidDB-10090-01079 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
9.12 |
Molecular Weight |
19454.08 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
FXYD domain-containing ion transport regulator 5 |
Protein Synonyms/Alias |
EF-8; Ion channel homolog RIC; Oncoprotein-induced protein 2; |
Gene Name |
Fxyd5 |
Gene Synonyms/Alias |
Oit2; |
Created Date |
15-JUL-1998 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
8 | Canonical | MSLSSRLCLLTIVAL | [1] | S-Palmitoylation | 166 | Canonical | IILTSGKCRQLSQFC | [1] | S-Palmitoylation | 173 | Canonical | CRQLSQFCLNRHR** | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). |
Sequence Annotation |
Topological domain: 22 145 Extracellular.
Transmembrane: 146 166 Helical.
Topological domain: 167 178 Cytoplasmic.
|
Protein Length |
178 AA. |
Protein Sequence
(Canonical) |
MSLSSRLCLL TIVALILPSR GQTPKKPTSI FTADQTSATT RDNVPDPDQT SPGVQTTPLI 60
WTREEATGSQ TAAQTETQQL TKMATSNPVS DPGPHTSSKK GTPAVSRIEP LSPSKNFMPP 120
SYIEHPLDSN ENNPFYYDDT TLRKRGLLVA AVLFITGIII LTSGKCRQLS QFCLNRHR 178
|
FASTA
(Canonical) |
>LipidDB-10090-01079|P97808
MSLSSRLCLLTIVALILPSRGQTPKKPTSIFTADQTSATTRDNVPDPDQTSPGVQTTPLI
WTREEATGSQTAAQTETQQLTKMATSNPVSDPGPHTSSKKGTPAVSRIEPLSPSKNFMPP
SYIEHPLDSNENNPFYYDDTTLRKRGLLVAAVLFITGIIILTSGKCRQLSQFCLNRHR
|
Gene Ontology |
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0005216; F:ion channel activity; IEA:InterPro |
Interpro |
InterPro; IPR000272; Ion-transport_regulator_FXYD |
Pfam |
|
SMART |
|
PROSITE |
|
PRINTS |
|