Lipid Modification Database
Tag Content
LipidDB ID
LipidDB-10090-00983
Entry Name
UniProt Accession
Theoretical PI
4.76
Molecular Weight
8527.91
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
Guanine nucleotide-binding protein G(T) subunit gamma-T1
Protein Synonyms/Alias
Transducin gamma chain;
Gene Name
Gngt1
Gene Synonyms/Alias
Gng1;
Created Date
01-NOV-1997
 Lipid Modification Sites 
 Position   Sequence Form   Peptide   References   Modification Type 
71
Canonical
FKELKGGCVIS****
[1]
S-Farnesylation
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Reference
[1] Kassai H, Satomi Y, Fukada Y, Takao T. Top-down analysis of proteinisoprenylation by electrospray ionization hybrid quadrupole time-of-flight tandemmass spectrometry; the mouse Tgamma protein. Rapid Commun Mass Spectrom.2005;19(2):269-74.[PMID:15609361]
Functional Description
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Sequence Annotation
Modified residue: 71 71 Cysteine methyl ester.
Protein Length
74 AA.
Protein Sequence
(Canonical)
MPVINIEDLT EKDKLKMEVD QLKKEVTLER MMVSKCCEEV RDYIEERSGE DPLVKGIPED  60
KNPFKELKGG CVIS                                                    74
FASTA
(Canonical)
>LipidDB-10090-00983|Q61012
MPVINIEDLTEKDKLKMEVDQLKKEVTLERMMVSKCCEEVRDYIEERSGEDPLVKGIPED
KNPFKELKGGCVIS
Gene Ontology
GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI
GO:0001917; C:photoreceptor inner segment; IEA:Ensembl
GO:0001750; C:photoreceptor outer segment; IEA:Ensembl
GO:0003924; F:GTPase activity; ISA:MGI
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW
GO:0010659; P:cardiac muscle cell apoptotic process; ISO:MGI
GO:0071456; P:cellular response to hypoxia; ISO:MGI
GO:0042462; P:eye photoreceptor cell development; IMP:MGI
GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI
GO:0006184; P:GTP catabolic process; ISA:GOC
GO:0007602; P:phototransduction; IMP:MGI
GO:0008104; P:protein localization; IMP:MGI
Interpro
InterPro; IPR015898; G-protein_gamma-like_dom
InterPro; IPR001770; Gprotein-gamma
Pfam
Pfam; PF00631; G-gamma;
SMART
SMART; SM00224; GGL;
PROSITE
PROSITE; PS50058; G_PROTEIN_GAMMA;
PRINTS
PRINTS; PR00321; GPROTEING;