LipidDB-10090-00596

Lipid Modification Database

Tag

Content

LipidDB ID

LipidDB-10090-00596

Entry Name

RCAS1_MOUSE

UniProt Accession

Q9D0V7; Q0VET4; Q3TVG2; Q3TWY4; Q9QYD0;

Theoretical PI

6.04

Molecular Weight

24319.43

Genbank Protein ID

AAG41054.1; AAF23857.1; BAB23277.1; BAE35132.1; BAE35657.1; AAI08398.1; AAI19119.1; AAI19121.1; AAI44741.1;

Genbank Nucleotide ID

AY009091; AF076524; AK004366; AK159499; AK160149; BC108397; BC119118; BC119120; BC144740;

Protein Name

Receptor-binding cancer antigen expressed on SiSo cells

Protein Synonyms/Alias

Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein;

Gene Name

Ebag9

Gene Synonyms/Alias

Rcas1;

Created Date

26-SEP-2003

Lipid Modification Sites
Position	Sequence Form	Peptide	References	Modification Type
14	Canonical	RLFKVCTCLATVFSF	[1]	S-Palmitoylation
27	Canonical	SFLKRLICRSGRGRK	[1]	S-Palmitoylation

Organism

Mus musculus (Mouse)

NCBI Taxa ID

10090

Reference

[1] Predicted from GPS-Lipid

Functional Description

May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases.

Sequence Annotation

Topological domain: 1 7 Extracellular.
Transmembrane: 8 27 Helical; Signal-anchor for type IIImembrane protein.
Topological domain: 28 213 Cytoplasmic.
Modified residue: 36 36 Phosphoserine.
Modified residue: 41 41 Phosphothreonine.
Modified residue: 94 94 Phosphotyrosine.

Protein Length

213 AA.

Protein Sequence
(Canonical)

MAITQFRLFK VCTCLATVFS FLKRLICRSG RGRKLSGDQI TLPTTVDYSS VPKQTDVEEW  60
TSWDEDAPTS VKIEGGNGNV ATQQNSLEQL EPDYFKDMTP TIRKTQKIVI KKREPLNFGV  120
PDGSTGFSSR LAATQDMPFI HQSSELGDLD TWQENSNAWE EEEDAAWQAE EVLRQQKIAD  180
REKRAAEQQR KKMEKEAQRL MKKEQNKIGV KLS                               213

FASTA
(Canonical)

>LipidDB-10090-00596|Q9D0V7
MAITQFRLFKVCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEW
TSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGV
PDGSTGFSSRLAATQDMPFIHQSSELGDLDTWQENSNAWEEEEDAAWQAEEVLRQQKIAD
REKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS

Gene Ontology

GO:0005925; C:focal adhesion; IEA:Ensembl
GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0005886; C:plasma membrane; IEA:Ensembl
GO:0030141; C:secretory granule; IEA:Ensembl
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW

Interpro

InterPro; IPR017025; Cancer-assoc_antigen_RCAS1

Pfam

SMART

PROSITE

PRINTS