| Tag |
Content |
LipidDB ID |
LipidDB-10090-00382 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
6.42 |
Molecular Weight |
25853.4 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Platelet-activating factor acetylhydrolase IB subunit gamma |
Protein Synonyms/Alias |
3.1.1.47; PAF acetylhydrolase 29 kDa subunit; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAFAH subunit gamma; |
Gene Name |
Pafah1b3 |
Gene Synonyms/Alias |
Pafahg; |
Created Date |
15-JUL-1998 |
| Lipid Modification Sites |
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
56 | Canonical | LVQLMHQCEIWRELF | [1] | S-Palmitoylation | 206 | Canonical | RLGYTPVCRALHSLL | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Wei X, Song H, Semenkovich CF. Insulin-regulated protein palmitoylationimpacts endothelial cell function. Arterioscler Thromb Vasc Biol. 2014Feb;34(2):346-54. doi: 10.1161/ATVBAHA.113.302848. Epub 2013 Dec 19.[ PMID:24357059]
|
Functional Description |
Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain. |
Sequence Annotation |
Active site: 48 48 Active site: 193 193 Active site: 196 196 Modified residue: 2 2 N-acetylserine.
|
Protein Length |
232 AA. |
Protein Sequence (Canonical) |
MSGEGENPAS KPTPVQDVQG DGRWMSLHHR FVADSKDKEP EVVFIGDSLV QLMHQCEIWR 60
ELFSPLHALN FGIGGDSTQH VLWRLENGEL EHIRPKIVVV WVGTNNHSHT AEQVTGGIKA 120
IVQLVNKLQP QARVVVLGLL PRGQHPNPLR EKNRQVNELV RAALAGYPRA HFLDADPGFV 180
HSDGTISHHD MYDYLHLSRL GYTPVCRALH SLLLRLLAQD QGQGIPLPET AS 232
|
FASTA (Canonical) |
>LipidDB-10090-00382|Q61205
MSGEGENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
ELFSPLHALNFGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKA
IVQLVNKLQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGYPRAHFLDADPGFV
HSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGIPLPETAS
|
Gene Ontology |
|
Interpro |
InterPro; IPR013831; SGNH_hydro-type_esterase_dom |
Pfam |
|
SMART |
|
PROSITE |
|
PRINTS |
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