| Tag |
Content |
LipidDB ID |
LipidDB-10090-00376 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
7.57 |
Molecular Weight |
134999.7 |
Genbank Protein ID |
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Genbank Nucleotide ID |
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Protein Name |
Catenin delta-2 |
Protein Synonyms/Alias |
Neural plakophilin-related ARM-repeat protein; NPRAP; Neurojungin; |
Gene Name |
Ctnnd2 |
Gene Synonyms/Alias |
Catnd2; Nprap; |
Created Date |
16-APR-2002 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
961 | Isoform 2 | DDTVTAVCCTLHEVI | [1] | S-Palmitoylation | 962 | Isoform 2 | DTVTAVCCTLHEVIT | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Brigidi GS, Sun Y, Beccano-Kelly D, Pitman K, Mobasser M, Borgland SL,Milnerwood AJ, Bamji SX. Palmitoylation of δ-catenin by DHHC5 mediatesactivity-induced synapse plasticity. Nat Neurosci. 2014 Apr;17(4):522-32. doi:10.1038/nn.3657. Epub 2014 Feb 23.[ PMID:24562000]
|
Functional Description |
May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. Functions as a transcriptional activator when bound to ZBTB33. |
Sequence Annotation |
Modified residue: 513 513 Phosphotyrosine.
Modified residue: 1098 1098 Phosphoserine.
|
Protein Length |
1247 AA. |
Protein Sequence
(Isoform 2) |
MFARKQSGAA PFGAMPVPDQ PPSASEKNSS LSPGLNTSNG DGSETETTSA ILASVKEQEL 60
QFERLTRELE AERQIVASQL ERCKLGSETG SMSSISSAGE QFHWQTQDGQ KDIEDELTTG 120
LELVDSCIRS LQESGILDPQ DYSTSERPSL LSQSALQLNS KPEGSFQYPA SYHSNQTLAL 180
GDTAPSQLPA RSTQARAAGQ SFSQGTTGRA GHLAGSEPAP PPPPPREPFA PSLGSAFHLP 240
DAPPAAAALY YSSSTLPAPP RGGSPLTTTQ GGSPTKLQRG GSAPEGAAYA APRGSSPKQS 300
PSRLAKSYST SSPINIVVSS AGLSPIRVTS PPTVQSTISS SPIHQLSSTI GTYATLSPTK 360
RLVHASEQYS KHSQELYATA TLQRPGSLAA GSRASYSSQH GHLAPELRAL QSPEHHIDPI 420
YEDRVYQKPP MRSLSQSQGD PLPPAHTGTF RTSTAPSSPG VDSVPLQRTG SQHGPQNAAA 480
ATFQRASYAA GPASNYADPY RQLQYCASVD SPYSKSGPAL PPEGTLARSP SIDSIQKDPR 540
EFGWRDPELP EVIQMLQHQF PSVQSNAAAY LQHLCFGDNK IKAEIRRQGG IQLLVDLLDH 600
RMTEVHRSAC GALRNLVYGK ANDDNKIALK NCGGIPALVR LLRKTTDLEI RELVTGVLWN 660
LSSCDALKMP IIQDALAVLT NAVIIPHSGW ENSPLQDDRK IQLHSSQVLR NATGCLRNVS 720
SAGEEARRRM RECDGLTDAL LYVIQSALGS SEIDSKTVEN CVCILRNLSY RLAAETSQGQ 780
HMGTDELDGL LCGETNGKDT ESSGCWGKKK KKKKSQDQWD GVGPLPDCAE PPKGIQMLWH 840
PSIVKPYLTL LSECSNPDTL EGAAGALQNL AAGSWKGSVY IRAAVRKEKG LPILVELLRI 900
DNDRVVCAVA TALRNMALDV RNKELIGKYA MRDLVHRLPG GNNSNNSGSK AMSDDTVTAV 960
CCTLHEVITK NMENAKALRD AGGIEKLVGI SKSKGDKHSP KVVKAASQVL NSMWQYRDLR 1020
SLYKKDGWSQ YHFVASSSTI ERDRQRPYSS SRTPSISPVR VSPNNRSASA PASPREMISL 1080
KERKTDYESA GNNATYHGTK GEHTSRKDTM TAQNTGVSTL YRNSYGAPAE DIKQNQVSTQ 1140
PVPQEPSRKD YETYQPFPNS TRNYDESFFE DQVHHRPPAS EYTMHLGLKS TGNYVDFYSA 1200
ARPYSELNYE TSHYPASPDS WV 1222
|
FASTA
(Isoform 2) |
>LipidDB-10090-00376|O35927-2
MFARKQSGAAPFGAMPVPDQPPSASEKNSSLSPGLNTSNGDGSETETTSAILASVKEQEL
QFERLTRELEAERQIVASQLERCKLGSETGSMSSISSAGEQFHWQTQDGQKDIEDELTTG
LELVDSCIRSLQESGILDPQDYSTSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLAL
GDTAPSQLPARSTQARAAGQSFSQGTTGRAGHLAGSEPAPPPPPPREPFAPSLGSAFHLP
DAPPAAAALYYSSSTLPAPPRGGSPLTTTQGGSPTKLQRGGSAPEGAAYAAPRGSSPKQS
PSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTK
RLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLAPELRALQSPEHHIDPI
YEDRVYQKPPMRSLSQSQGDPLPPAHTGTFRTSTAPSSPGVDSVPLQRTGSQHGPQNAAA
ATFQRASYAAGPASNYADPYRQLQYCASVDSPYSKSGPALPPEGTLARSPSIDSIQKDPR
EFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDH
RMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWN
LSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVS
SAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQ
HMGTDELDGLLCGETNGKDTESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWH
PSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKGSVYIRAAVRKEKGLPILVELLRI
DNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNSGSKAMSDDTVTAV
CCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLR
SLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISL
KERKTDYESAGNNATYHGTKGEHTSRKDTMTAQNTGVSTLYRNSYGAPAEDIKQNQVSTQ
PVPQEPSRKDYETYQPFPNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDFYSA
ARPYSELNYETSHYPASPDSWV
|
Gene Ontology |
GO:0030054; C:cell junction; IEA:UniProtKB-KW GO:0005634; C:nucleus; IEA:UniProtKB-KW GO:0007612; P:learning; IMP:MGI GO:0001763; P:morphogenesis of a branching structure; IDA:MGI GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW GO:0048167; P:regulation of synaptic plasticity; IMP:MGI GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW |
Interpro |
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Pfam |
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SMART |
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PROSITE |
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PRINTS |
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