| Tag |
Content |
LipidDB ID |
LipidDB-10090-00344 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.65 |
Molecular Weight |
27189.04 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Endothelial protein C receptor |
Protein Synonyms/Alias |
Activated protein C receptor; APC receptor; Centrocyclin; Centrosomal protein CCD41; Endothelial cell protein C receptor; CD201; |
Gene Name |
Procr |
Gene Synonyms/Alias |
Epcr; |
Created Date |
27-APR-2001 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
19 | Canonical | LLPGCALCNSDGSQS | [1] | S-Palmitoylation | 236 | Canonical | VAVGIFMCTSGRRC* | [1] | S-Palmitoylation | 242 | Canonical | MCTSGRRC******* | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. |
Sequence Annotation |
Topological domain: 18 214 Extracellular.
Transmembrane: 215 235 Helical.
Topological domain: 236 242 Cytoplasmic.
|
Protein Length |
242 AA. |
Protein Sequence
(Canonical) |
MLTKFLPLLL LLLPGCALCN SDGSQSLHML QISYFQDNHH VRHQGNASLG KLLTHTLEGP 60
SQNVTILQLQ PWQDPESWER TESGLQIYLT QFESLVKLVY RERKENVFFP LTVSCSLGCE 120
LPEEEEEGSE PHVFFDVAVN GSAFVSFRPK TAVWVSGSQE PSKAANFTLK QLNAYNRTRY 180
ELQEFLQDTC VEFLENHITT QNMKGSQTGR SYTSLVLGIL MGCFIIAGVA VGIFMCTSGR 240
RC 242
|
FASTA
(Canonical) |
>LipidDB-10090-00344|Q64695
MLTKFLPLLLLLLPGCALCNSDGSQSLHMLQISYFQDNHHVRHQGNASLGKLLTHTLEGP
SQNVTILQLQPWQDPESWERTESGLQIYLTQFESLVKLVYRERKENVFFPLTVSCSLGCE
LPEEEEEGSEPHVFFDVAVNGSAFVSFRPKTAVWVSGSQEPSKAANFTLKQLNAYNRTRY
ELQEFLQDTCVEFLENHITTQNMKGSQTGRSYTSLVLGILMGCFIIAGVAVGIFMCTSGR
RC
|
Gene Ontology |
GO:0005813; C:centrosome; IDA:MGI GO:0070062; C:extracellular vesicular exosome; IEA:Ensembl GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0008022; F:protein C-terminus binding; ISS:MGI GO:0019882; P:antigen processing and presentation; IEA:InterPro GO:0007596; P:blood coagulation; IEA:UniProtKB-KW GO:0006955; P:immune response; IEA:InterPro GO:0050819; P:negative regulation of coagulation; TAS:MGI |
Interpro |
|
Pfam |
|
SMART |
|
PROSITE |
|
PRINTS |
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