| Tag |
Content |
LipidDB ID |
LipidDB-10090-00191 |
Entry Name |
|
UniProt Accession |
|
Theoretical PI |
5.01 |
Molecular Weight |
51848.0 |
Genbank Protein ID |
|
Genbank Nucleotide ID |
|
Protein Name |
Protein disulfide-isomerase TMX3 |
Protein Synonyms/Alias |
5.3.4.1; Thioredoxin domain-containing protein 10; Thioredoxin-related transmembrane protein 3; |
Gene Name |
Tmx3 |
Gene Synonyms/Alias |
Kiaa1830; Txndc10; |
Created Date |
24-MAY-2005 |
| Lipid Modification Sites |
|---|
| Position |
Sequence Form |
Peptide |
References |
Modification Type |
16 | Canonical | SWAALRLCAAVILLD | [1] | S-Palmitoylation | 56 | Canonical | VDFYAPWCGHCKKLE | [1] | S-Palmitoylation |
|
Organism |
Mus musculus (Mouse) |
NCBI Taxa ID |
10090 |
Reference |
[1] Predicted from GPS-Lipid
|
Functional Description |
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase (By similarity). |
Sequence Annotation |
Topological domain: 30 378 Lumenal.
Transmembrane: 379 399 Helical.
Topological domain: 400 456 Cytoplasmic.
Domain: 30 131 Thioredoxin.
Motif: 453 456 Di-lysine motif.
|
Protein Length |
456 AA. |
Protein Sequence
(Canonical) |
MANAVGRRSW AALRLCAAVI LLDLAVCKGF VEDLNESFKD NRKDDIWLVD FYAPWCGHCK 60
KLEPIWNEVG LEMKSIGSPV KVGKMDATSY SSIASEFGVR GYPTIKLLKG DLAYNYRGPR 120
TKDDIIEFAH RVSGALIRPL PSQQMFDHVR KRHRVFFVYI GGESPLKEKY IDAASELIVY 180
TYFFSASEDV VPEYVTLKEM PAVLVFKDDT YFVYDEYEDG DLSSWISRER FQNYLTMDGF 240
LLYELGDTGK LVAIAVIDEK NTSLEHTRLK SIIQEVARDF RDHFHRDFQF GHMDGNDYIN 300
TLLMDELTVP TIVVLNTSNQ QYFLLDRHIK DASDMVQFIN SILDGTVPAQ GGDSIFQRLK 360
RIVFDAKSTI VSIFKSSPLM GCFLFGLPLG VISIMCYGIY TADTDGGYIE ERYEVSKSEM 420
ENQEQIEESK EQESSSGGSL APTVQEPKDV LEKKKD 456
|
FASTA
(Canonical) |
>LipidDB-10090-00191|Q8BXZ1
MANAVGRRSWAALRLCAAVILLDLAVCKGFVEDLNESFKDNRKDDIWLVDFYAPWCGHCK
KLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPR
TKDDIIEFAHRVSGALIRPLPSQQMFDHVRKRHRVFFVYIGGESPLKEKYIDAASELIVY
TYFFSASEDVVPEYVTLKEMPAVLVFKDDTYFVYDEYEDGDLSSWISRERFQNYLTMDGF
LLYELGDTGKLVAIAVIDEKNTSLEHTRLKSIIQEVARDFRDHFHRDFQFGHMDGNDYIN
TLLMDELTVPTIVVLNTSNQQYFLLDRHIKDASDMVQFINSILDGTVPAQGGDSIFQRLK
RIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSEM
ENQEQIEESKEQESSSGGSLAPTVQEPKDVLEKKKD
|
Gene Ontology |
GO:0009986; C:cell surface; IDA:MGI GO:0005783; C:endoplasmic reticulum; IBA:RefGenome GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome GO:0045454; P:cell redox homeostasis; IEA:InterPro GO:0006457; P:protein folding; IBA:RefGenome GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome |
Interpro |
|
Pfam |
|
SMART |
|
PROSITE |
|
PRINTS |
|