LipidDB ID

LipidDB-10090-00155

Entry Name

UniProt Accession

O70439;

Theoretical PI

5.6

Molecular Weight

29820.71

Genbank Protein ID

AAC15971.1;

Genbank Nucleotide ID

AF056323;

Protein Name

Syntaxin-7

Protein Synonyms/Alias

Gene Name

Stx7

Gene Synonyms/Alias

Syn7;

Created Date

11-FEB-2002

Organism

Mus musculus (Mouse)

NCBI Taxa ID

10090

Reference

[1] Predicted from GPS-Lipid

Functional Description

May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity).

Sequence Annotation

Topological domain: 2 238 Cytoplasmic.
Transmembrane: 239 259 Helical; Anchor for type IV membraneprotein.
Topological domain: 260 261 Vesicular.
Domain: 165 227 t-SNARE coiled-coil homology.
Modified residue: 2 2 N-acetylserine.
Modified residue: 45 45 Phosphoserine.
Modified residue: 79 79 Phosphothreonine.
Modified residue: 125 125 Phosphoserine.
Modified residue: 126 126 Phosphoserine.
Modified residue: 129 129 Phosphoserine.
Modified residue: 205 205 Phosphoserine.

Protein Length

261 AA.

Protein Sequence
(Canonical)

FASTA
(Canonical)

Gene Ontology

GO:0005768; C:endosome; IEA:UniProtKB-KW
GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW
GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI
GO:0031201; C:SNARE complex; IBA:RefGenome
GO:0005484; F:SNAP receptor activity; IBA:RefGenome
GO:0000149; F:SNARE binding; ISO:MGI
GO:0006886; P:intracellular protein transport; IBA:RefGenome
GO:0016079; P:synaptic vesicle exocytosis; IBA:RefGenome

Interpro

InterPro; IPR006012; Syntaxin/epimorphin_CS
InterPro; IPR006011; Syntaxin_N
InterPro; IPR010989; t-SNARE
InterPro; IPR000727; T_SNARE_dom

Pfam

Pfam; PF05739; SNARE;

SMART

SMART; SM00503; SynN;
SMART; SM00397; t_SNARE;

PROSITE

PROSITE; PS00914; SYNTAXIN;
PROSITE; PS50192; T_SNARE;

PRINTS